Utilization of Different Prebiotics by<i>Lactobacillus</i>Spp. and<i>Lactococcus</i>Spp.

Mandadzhieva, Tanya; Ignatova-Ivanova, Tsveteslava; Kambarev, Stanimir; Iliev, Ilia; Ivanova, I.

doi:10.5504/bbeq.2011.0132

Cited by 19 publications

(11 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The findings also showed, the supernatant of L. rhamnosus followed by L. fermentum with inulin have potent inhibitory effects against Gram-positive E. faecalis. In the study by Mandadzieva et al, antimicrobial activity of different strains of Lactobacillus against Enterobacter aerogenes was increased in the presence of oligosaccharides [34,35] which was similar with our findings. The study found that the adsorption of abnormal sugars could increase the production of antimicrobial agents on specific pathways [34,35].…”

Section: Discussionsupporting

confidence: 93%

“…In the study by Mandadzieva et al, antimicrobial activity of different strains of Lactobacillus against Enterobacter aerogenes was increased in the presence of oligosaccharides [34,35] which was similar with our findings. The study found that the adsorption of abnormal sugars could increase the production of antimicrobial agents on specific pathways [34,35]. The mechanism of this stimulatory activity and how the lactic acid bacteria use oligosaccharides is still unclear due to the unique characteristics of the strain.…”

Section: Discussionsupporting

confidence: 93%

“…In the present study, raffinose, trehalose, riboflavin, citrate, inulin, and sorbitol was used as prebiotic. These prebiotics were used in lower concentrations (0.3%) than previous studies (0.5-5%) [34,35].The results show the efficiency of prebiotics at lower concentration. Our results showed that cell-free supernatant of L. rhamnosus with citrate or trehalose and L. fermentum with trehalose have the best antibacterial activity against Gram-negative A. baumannii.…”

Section: Discussionmentioning

confidence: 57%

See 2 more Smart Citations

Antibacterial and Antibiofilm Effects of Synbiotics against Multidrug-Resistant bacteria: Acinetobacter baumannii and Enterococcus faecalis

Laal-Kargar

Dolatabadi

Mohtashami

2020

Preprint

View full text Add to dashboard Cite

Background: Acinetobacter baumannii and Enterocoocus faecalis increase their resistance against antibiotic by producing biofilm. Antibiotic resistance has become a massive public health threat that require novel effective antibacterial and antibiofilm alternatives. The use of probiotics is interested to prevent and control certain infections. The objective of this study was to investigate the antibacterial and antibiofilm property of probiotics and synbiotics against multidrug-resistant A. baumannii and E. faecalis. Methods: The antimicrobial and the antibiofilm activities of cell- free supernatants of four strains of Lactobacillus against 20 clinical multi-drug resistant (MDR) isolates of Acinetobacter baumannii and Enterocoocus faecalis were determined in the presence of 0.3% of sorbitol, raffinose, citrate, trehalose, inulin, and riboflavin using well diffusion agar and micro-dilution method. Results: The cell- free supernatant of L. rhamnosus with citrate and trehalose showed the best antibacterial activity against MDR A. baumannii (28.8±2.1mm, 1.128 μL/mL), and L. rhamnosus with all of prebiotics against MDR E. faecalis (29.8±0 mm, 1.128 μL/mL) compare to probiotic alone. The prebiotics could improve the inhibitory effect of probiotics against the Gram-negative A. baumannii higher than Gram-positive E. faecalis. Biofilm formation was reduced in both pathogens in presence of synbiotics. L. plantarum with riboflavin and L. rhamnosus with or without inulin potently inhibits E. faecalis (50±0.86%) and A. baumannii (75±6.5%) biofilm formation, respectively. Conclusions: The results of current study support the antibiofilm activity of metabolites produced by synbiotics, and suggest their use as suitable adjuvants as well as biocontrol agents for treatment.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 57%

See 1 more Smart Citation

Antibacterial and Antibiofilm Effects of Synbiotics against Multidrug-Resistant bacteria: Acinetobacter baumannii and Enterococcus faecalis

Laal-Kargar

Dolatabadi

Mohtashami

2020

Preprint

View full text Add to dashboard Cite

show abstract

“…In vitro growth assays and human trials that explored changes in gut microbiota composition after XOS intake also pointed to XOSs as prebiotic polysaccharides that stimulate the growth of certain lactobacilli [ 26 ]. Notwithstanding, the capacity to ferment XOSs by lactobacilli seems to be limited [ 23 , 36 ].…”

Section: Discussionmentioning

confidence: 99%

Metabolic Profiling of Xylooligosaccharides by Lactobacilli

et al. 2020

Self Cite

View full text Add to dashboard Cite

Three lactic acid bacteria (LAB) strains identified as Lactobacillus plantarum, Lactobacillus brevis, and Lactobacillus sakei isolated from meat products were tested for their ability to utilize and grow on xylooligosaccharides (XOSs). The extent of carbohydrate utilization by the studied strains was analyzed by HPLC. All three strains showed preferences for the degree of polymerization (DP). The added oligosaccharides induced the LAB to form end-products of typical mixed-acid fermentation. The utilization of XOSs by the microorganisms requires the action of three important enzymes: β-xylosidase (EC 3.2.1.37) exo-oligoxylanase (EC 3.2.1.156) and α-L-arabinofuranosidase (EC 3.2.1.55). The presence of intracellular β-D-xylosidase in Lb. brevis, Lb. plantarum, and Lb. sakei suggest that XOSs might be the first imported into the cell by oligosaccharide transporters, followed by their degradation to xylose. The studies on the influence of XOS intake on the lipids of rat liver plasma membranes showed that oligosaccharides display various beneficial effects for the host organism, which are probably specific for each type of prebiotic used. The utilization of different types of oligosaccharides may help to explain the ability of Lactobacillus strains to compete with other bacteria in the ecosystem of the human gastrointestinal tract.

show abstract

“…Moreover, Lactobacillus spp. cultured and fermented with FOS showed antimicrobial activity against Listeria innocua and Enterobacter aerogenes (Mandadzhieva et al, 2011).…”

Section: Furthermore Intestinal Bacteria Including Lactobacillus Andmentioning

confidence: 99%

Microbiota‐dependent and ‐independent effects of dietary fibre on human health

Cai

Folkerts

et al. 2019

British J Pharmacology

102

View full text Add to dashboard Cite

Dietary fibre, such as indigestible oligosaccharides and polysaccharides, occurs in many foods and has gained considerable importance related to its beneficial effects on host health and specific diseases. Dietary fibre is neither digested nor absorbed in the small intestine and modulates the composition of the gut microbiota. New evidence indicates that dietary fibre also interacts directly with the epithelium and immune cells throughout the gastrointestinal tract by microbiota‐independent effects. This review focuses on how dietary fibre improves human health and the reported health benefits that are connected to molecular pathways, in (a) a microbiota‐independent manner, via interaction with specific surface receptors on epithelial and immune cells regulating intestinal barrier and immune function, and (b) a microbiota‐dependent manner via maintaining intestinal homeostasis by promoting beneficial microbes, including Bifidobacteria and Lactobacilli, limiting the growth, adhesion, and cytotoxicity of pathogenic microbes, as well as stimulating fibre‐derived microbial short‐chain fatty acid production. Linked Articles This article is part of a themed section on The Pharmacology of Nutraceuticals. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v177.6/issuetoc

show abstract

Utilization of Different Prebiotics byLactobacillusSpp. andLactococcusSpp.

Cited by 19 publications

References 8 publications

Antibacterial and Antibiofilm Effects of Synbiotics against Multidrug-Resistant bacteria: Acinetobacter baumannii and Enterococcus faecalis

Antibacterial and Antibiofilm Effects of Synbiotics against Multidrug-Resistant bacteria: Acinetobacter baumannii and Enterococcus faecalis

Metabolic Profiling of Xylooligosaccharides by Lactobacilli

Microbiota‐dependent and ‐independent effects of dietary fibre on human health

Contact Info

Product

Resources

About