Utilization of hormone replacement therapy in Spain: Trends in the period 2000–2014

Martínez, Laura Baladé; Corominas, Dolores Montero; Saint-Gerons, Diego Macías

doi:10.1016/j.medcle.2016.10.019

Cited by 8 publications

(12 citation statements)

References 28 publications

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“…The use of MHT in Sweden changed significantly from 2000 to 2021, with a rapid decrease in use in all age groups after the publication of the WHI, HERS and Million Women studies in 2002 to 2003 (86,89,91); this result is in line with previous studies (112,(115)(116)(117)(150)(151)(152)(153).…”

Section: Mht Use Over Time (Paper Ii)supporting

confidence: 84%

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Epidemiological and Clinical Aspects of Hormonal Contraception and Menopausal Hormone Therapy in Women

Sundell

2023

Linköping University Medical Dissertations

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BackgroundThe main indication for therapy with female sex hormones in younger women is contraception, whereas women around and after menopause might use menopausal hormone therapy (MHT) to manage vasomotor symptoms. The use of hormonal contraception and MHT, both referred to as hormone therapy in this thesis, has changed over time and varies in different age groups and populations depending on indications, definitions of use, current knowledge, and clinical guidelines. The use of oestrogen may increase the risk of venous thromboembolism and therefore combined hormonal contraceptives (CHC) are not recommended to women with obesity. Women with early or premature menopause are recommended hormone therapy at least until the normal age of menopause to avoid the increased morbidity and mortality caused by oestrogen deficiency.

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Section: Mht Use Over Time (Paper Ii)supporting

confidence: 84%

“…The same pattern, with a rapid decrease and following stabilisation of MHT use, has been described in Korea (150), Spain (151), Australia (152) and New Zealand (153). These studies mainly estimated the use of MHT based on prescriptions or dispensation of DDD´s of MHT.…”

Section: Incidence Of Mht Usementioning

confidence: 59%

Epidemiological and Clinical Aspects of Hormonal Contraception and Menopausal Hormone Therapy in Women

Sundell

2023

Linköping University Medical Dissertations

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“…However, in Spain, the most common OC used is combined OC (estrogen + progestin) 8 . In the same way, the most common HT used by women without hysterectomy is estrogen combined with progesterone 9,10 specifically tibolone, which exhibits a combination of estrogenic and progestonic activity, with a slight androgenic activity 11 . The second one is that the data on OC and HT consumption were self-reported and retrospectively collected, which exposed our results to possible recall bias.…”

Section: Discussionmentioning

confidence: 99%

“…However, in 2002, the Women's Health Initiative (WHI) study reported that HT could be harmful to health, eventually leading to a dramatic decrease in its usage, [22][23][24] including in Spain. 9,25,26 In this sense, several studies reported that this therapy increased the risk of breast cancer development, 27,28 although there are controversial results. 29,30 In terms of its potential role in breast cancer prognosis, it remains unclear if HT use is associated with better or worse breast cancer prognosis, or if it may have prognostic value only for certain subgroups of breast cancer patients.…”

mentioning

confidence: 99%

Effect of the use of prediagnosis hormones on breast cancer prognosis: MCC-Spain study

et al. 2022

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“…Hormonal replacement therapy appeared much later than hormonal contraceptives, but its usage was amplified via private practicing doctors. This eventually resulted in higher consumption for women in higher socioeconomic levels; in 2001, when most women born after 1950 had not reached menopause, the Women's Health Initiative study found an association between hormonal replacement therapy and several cancers [25] and other chronic diseases [26], leading to a dramatic decrease in hormone replacement therapy in Spain [27].…”

Section: Preterm and Post-term Newbornmentioning

confidence: 99%

Changes in individual and contextual socio-economic level influence on reproductive behavior in Spanish women. The MCC-Spain study

Gómez‐Acebo

Dierssen-Sotos

Palazuelos

et al. 2020

Preprint

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Background The association between socioeconomic level and reproductive factors has been widely studied. For example, it is well known that women with lower socioeconomic status (SES) tend to have more children, the age at first-born being earlier. However, less is known about to what extent the great socioeconomic changes occurred in a country (Spain) could modify women reproductive factors. The main purpose of this article is to analyze the influence of individual and contextual socioeconomic levels on reproductive factors in Spanish women, and to explore whether this influence has changed over the last decades. Methods We performed a cross-sectional design using data from 2038 women recruited as population-based controls in an MCC-Spain case-control study. Results Higher parent’s economic level, education level, occupational level and lower urban vulnerability were associated with higher age at first delivery and lower number of pregnancies. These associations were stronger for women born after 1950: women with unfinished primary education had their first delivery six years before women with high education if they were born after 1950 (23.4 vs. 29.8 years) but only three years before if they were born before 1950 (25.7 vs. 28.0 years). For women born after 1950, the number of pregnancies dropped from 2.1 (unfinished primary school) to 1.7 (high education), whereas it remained almost unchanged in women born before 1950. Conclusions Reproductive behavior was associated with both individual and area-level socio-economic indicators. Such association was stronger for women born after 1950 regarding age at first delivery and number of pregnancies and for women born before 1950 regarding consumption of hormonal contraceptives or postmenopausal therapy.

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Utilization of hormone replacement therapy in Spain: Trends in the period 2000–2014

Cited by 8 publications

References 28 publications

Epidemiological and Clinical Aspects of Hormonal Contraception and Menopausal Hormone Therapy in Women

Epidemiological and Clinical Aspects of Hormonal Contraception and Menopausal Hormone Therapy in Women

Effect of the use of prediagnosis hormones on breast cancer prognosis: MCC-Spain study

Changes in individual and contextual socio-economic level influence on reproductive behavior in Spanish women. The MCC-Spain study

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