Utilization of neurosurgical perioperative antimicrobial prophylaxis in a Chinese teaching hospital

Zhang, Weiwei; Meng, Huijie; Mao, Chien-Tai; Yong-fang, HU

doi:10.1007/s11096-021-01233-2

Cited by 4 publications

(5 citation statements)

References 48 publications

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“…Other studies revealed that a single intravenous dose or within 24 h administration of antimicrobial is enough to prevent postoperative infection in clean operations. 23 In line with prior studies, our results showed that QCC intervention has no effect on the incidence of SSI, other surgical complications and antimicrobial-related ADR.…”

Section: Strengths and Limitationssupporting

confidence: 91%

Sustained Improvement of Appropriateness in Surgical Antimicrobial Prophylaxis with the Application of Quality Control Circle

Zou¹,

Zhong²,

Liu³

et al. 2023

RMHP

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Quality control circle (QCC) has acquired success in many fields in healthcare industry as a process management tool, whereas its efficacy in surgical antimicrobial prophylaxis (SAP) remains unknown. This study aimed to implement QCC interventions to improve the appropriateness of SAP. Methods: A QCC activity team was established to grasp the current situation of SAP in clean surgery procedure, set target, formulate corresponding countermeasures and implement and review them in stages. The plan-do-check-act (PDCA) method was cyclically applied. Results:The appropriateness of antibiotic prophylaxis before (January to December 2020) and after (January to December 2021) the implementation of QCC activities were evaluated based on relevant international and Chinese SAP guidelines. The overall SAP appropriateness was significantly improved from 68.72% before QCC to 93.7% post QCC implementation (P<0.01). A significant improvement (P<0.05) was also determined for each category: selection (from 78.82% to 96.06%), duration (from 90.15% to 96.46%), indication (from 94.09% to 97.64%), timing of first dose (from 96.55% to 99.21%), antimicrobial usage (from 96.8% to 99.41%), redosing of antimicrobial (from 96.55% to 99.21%). Conclusion: Implementation of a QCC program can optimize the use of antibiotics and improve the appropriateness of SAP and is of practical importance to their standardization.

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Section: Strengths and Limitationssupporting

confidence: 91%

Sustained Improvement of Appropriateness in Surgical Antimicrobial Prophylaxis with the Application of Quality Control Circle

Zou¹,

Zhong²,

Liu³

et al. 2023

RMHP

View full text Add to dashboard Cite

show abstract

“…However, in almost 10% of the procedures in our study, the duration of PAP exceeded this time limit. Previous studies demonstrated that prolonged PAP can alter the institutional antibiogram and an individual's microbiome, which can lead to the emergence of bacterial resistance and may increase the incidence of antibiotic-associated complications [22,23]. Other studies revealed that a single intravenous dose or within 24 h administration of PAP is enough to prevent postoprerative infection in clean operations [23].…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies demonstrated that prolonged PAP can alter the institutional antibiogram and an individual's microbiome, which can lead to the emergence of bacterial resistance and may increase the incidence of antibiotic-associated complications [22,23]. Other studies revealed that a single intravenous dose or within 24 h administration of PAP is enough to prevent postoprerative infection in clean operations [23]. In line with prior studies, our results showed that shorter antimicrobial prophylaxis after QCC intervention has no effect on the incidence of SSI, other surgical complications and antibiotic-related ADR.…”

Section: Discussionmentioning

confidence: 99%

Appropriateness and adherence to guidelines in perioperative antimicrobial prophylaxis in patients undergoing clean surgery: results from a Quality Control Circle intervention

Zou¹,

Zhong²,

Liu³

et al. 2022

Preprint

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Background: Appropriate implementation of perioperative antimicrobial prophylaxis in surgery is considered an effective measure to prevent the incidence of surgical site infection and the emergence of antimicrobial-resistant bacteria. To reduce the emergence of antimicrobial-resistant bacteria, there is a need to improve the correct implementation of PAP. Methods: A QCC activity team was established to grasp the current situation of PAP in clean surgery procedure, set target, formulated corresponding countermeasures and implement and review them in stages. The plan-do-check-act method was cyclically applied. The appropriateness of PAP before (July to December 2018) and after (April to September 2019) the implementation of QCC activities were evaluated based on relevant international and Chinese perioperative antimicrobial prophylaxis guidelines. Results: The appropriate rate of PAP was significantly improved from 68.72% (n=406) before QCC to 93.7% (n=508) post QCC implementation (P＜0.01). A significant improvement (P＜0.05) was also determined for each category: selection (from 78.82 to 96.06%), duration (from 90.15 to 96.46%), indication (from 94.09 to 97.64%), timing of first dose (from 96.55 to 99.21%), antibiotic usage (from 96.8 to 99.41%), re-dosing of antibiotic (from 96.55 to 99.21%). Conclusions: The appropriate application of PAP is improved through QCC activities, providing a useful reference for the prevention of antimicrobial-resistant bacteria and the development of medical quality improvement activities.

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“…However, in almost 10% of the procedures in our study, the duration of SAP exceeded this time limit. Previous studies demonstrated that prolonged SAP can alter the institutional antibiogram and an individual's microbiome, which can lead to the emergence of bacterial resistance and may increase the incidence of antimicrobial-associated complications [23].…”

Section: Strengths and Limitationsmentioning

confidence: 99%

Sustained improvement of appropriateness in surgical antimicrobial prophylaxis with the application of quality control circle

Zou¹,

Zhong²,

Liu³

et al. 2022

Preprint

View full text Add to dashboard Cite

Administration of surgical antimicrobial prophylaxis (SAP) is considered one of the most effective measures to reduce the incidence of surgical site infection (SSI) after various surgical procedures. Quality control circle (QCC) has acquired success in many fields in healthcare industry as a process management tool, whereas its efficacy in SAP remains unknown. Our present study utilized the QCC activity to improve the appropriate administration of SAP. A QCC activity team was established to grasp the current situation of SAP in clean surgery procedure, set target, formulated corresponding countermeasures and implement and review them in stages. The plan-do-check-act (PDCA) method was cyclically applied. The appropriateness of SAP before (July to December 2018) and after (January to June 2019) the implementation of QCC activities were evaluated based on relevant international and Chinese SAP guidelines. The appropriate rate of SAP was significantly improved from 68.72% before QCC to 93.7% post QCC implementation (P༜0.01). A significant improvement (P༜0.05) was also determined for each category: selection (from 78.82 to 96.06%), duration (from 90.15 to 96.46%), indication (from 94.09 to 97.64%), timing of first dose (from 96.55 to 99.21%), antimicrobial usage (from 96.8 to 99.41%), re-dosing of antimicrobial (from 96.55 to 99.21%). The appropriate application of SAP is improved through QCC activities, providing a useful reference for the prevention of antimicrobial misuse and overuse.

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Utilization of neurosurgical perioperative antimicrobial prophylaxis in a Chinese teaching hospital

Cited by 4 publications

References 48 publications

Sustained Improvement of Appropriateness in Surgical Antimicrobial Prophylaxis with the Application of Quality Control Circle

Sustained Improvement of Appropriateness in Surgical Antimicrobial Prophylaxis with the Application of Quality Control Circle

Appropriateness and adherence to guidelines in perioperative antimicrobial prophylaxis in patients undergoing clean surgery: results from a Quality Control Circle intervention

Sustained improvement of appropriateness in surgical antimicrobial prophylaxis with the application of quality control circle

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