Utilization of potentially inappropriate medications in elderly patients in a tertiary care teaching hospital in India

Jhaveri, Binit N; Patel, Tejas; Barvaliya, Manish; Tripathi, C. B.

doi:10.4103/2229-3485.140562

Cited by 26 publications

(19 citation statements)

References 29 publications

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“…2,20 less when compared with the Venkateswamurthy et al 19 Average age of patients was 69.03, it was similar to that of the Ramesh KT et al 18 and almost near to the Binit NJ et al 6 The average number of drugs per prescription was 9.6, which was similar to Lordu et al 2 but when compared with other studies this number was 4 times more. 2,6,1820 Among 140 prescriptions 128 (91.4%) prescriptions were found as polypharmacy prescriptions, this number was larger than the other studies. Prescription with polypharmacy leads to the ADRs, DrugDrug interactions, and increased risk of hospitalization, adherence, and medication errors.…”

supporting

confidence: 67%

“…Higher PIMs were observed from Beers criteria than the PRISCUS list (17 Vs 10). This was not similar to Binit NJ et al 6 And totally 39 prescription were with PIMs and rest of the prescriptions 101 were free from PIMs. But, in Binit NJ et al almost all cases had at least one inappropriate medication in their observa tion.…”

mentioning

confidence: 76%

“…In India there are no such tools to identify the PIMs. 6,2124 Principally, clinicians do not have evidences of the benefits and risks of the drug therapy, why because older people are excluded from clinical trials due to some barriers include: comorbidity, cognitive impairment, difficulty in attending for monitoring and finally ethical issues.…”

Section: Introductionmentioning

confidence: 99%

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A Prospective Study on inappropriate Drug utilization in Geriatric Patients at A Tertiary Care Teaching Hospital

Battula¹,

Reddy²,

Thammisetty³

et al. 2016

IJOPP

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Background: Prescribing to the older people is challenging. Pharmacokinetics and pharmacodynamic changes, chronic diseases, polypharmacy prescribing, potentially inappropriate medication (PIMs) prescribing, medication errors, adverse drug reactions, drug interactions, inappropriate prescribing or suboptimal prescribing are causes for challenge. It may lead to non-adherence, increase morbidity, length of hospitalization, poor quality of life, and finally death may occur. Method: A Prospective observational study was conducted in General Medicine department, for a period of 6 months. Patients of either gender who are above 65 years of age in general medicine in-patient ward with or without co-morbidities were included in the study; we excluded seriously ill and patients unable to communicate and Patients unwilling to participate in the study. Results: Total 140 geriatrics patients were admitted. In this study we observed that almost all prescriptions were with polypharmacy. PIMs observed from Beers criteria (17) and less in PRISCUS list (10). From both the lists 4 PIMs observed as same medications. Totally in 140 patients, 101 patients prescriptions were free from the PIMs, rest of the all potentially inappropriate prescriptions (PIPs). Conclusion: Inappropriate prescribing in geriatric patients is highly prevalent.

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supporting

confidence: 67%

mentioning

confidence: 76%

Section: Introductionmentioning

confidence: 99%

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A Prospective Study on inappropriate Drug utilization in Geriatric Patients at A Tertiary Care Teaching Hospital

Battula¹,

Reddy²,

Thammisetty³

et al. 2016

IJOPP

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“…Several studies carried out in elderly patients around the world show that prevalence of use of inappropriate medications ranges from (25%-49%) (14). A study from India shows prevalence of use of at least one potentially inappropriate medication in elderly to be 87.3% (15). Another study reports the prevalence of 40% of at least one, 22.61% of two and 3.57% of three or more potentially inappropriate medication use (8).…”

Section: Discussionmentioning

confidence: 99%

The study on prevalence of polypharmacy in elderly patients presenting for first time to the geriatric clinic of a tertiary care hospital in Kerala

Rajeev

Paul

George

et al. 2018

ijmsci

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Introduction : Elderly patients are the most common group who use heath care facilities. This study assesses the prevalence of polypharmacy and use of potentially inappropriate medications in elderly patients presenting to the geriatric clinic of a tertiary care hospital in Kerala for first time. Materials and methods : The study was a hospital based retrospective study. The data from patients presenting to Geriatrics clinic from period of 1 st January 2016 to 31 st December 2016 were retrieved from the medical records and assessed for polypharmacy (taking >5 medications at a time) and potentially inappropriate drugs in accord with modified 2012 Beer’s criteria. Results : A total of 275 patients were included in the study of which 110 (40%) were males and 165 (60%) were females. The prevalence of polypharmacy found to be 22.9%. 63 out of total 275 patients took more than 5 medications at a time. 81 (29.5%) out of 275 patients had at least one potentially inappropriate medication. Conclusion : The prescription of potentially inappropriate medications is a serious problem which can affect overall quality of health care. Hence regular medication review and reconciliation practices should be implemented to prevent this to an extent.

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“…Due to the demographic, social, economic, and cultural changes, the aging phenomenon is increasingly emerging as a social issue (1). The global growth rate of the elderly (1.9%) is higher than the general population (1.2%) (2). The United Nations estimates that the elderly will account for 11% of the world's total population (about 800 million), rising to about 2 billion in 2050 (3).…”

Section: Introductionmentioning

confidence: 99%

Drug Use Pattern Among Elderly People Referred to the Retirement Centers

et al. 2018

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Background: Elderly people are more susceptible to common chronic diseases based on their age-related physiological changes and also use drugs more commonly, than younger people. Objectives: The aim of the present study was to determine the pattern of drug use and related factors in elderly people who referred to the retirement centers covered by the national retirement fund in Rasht. Methods: This cross-sectional study was conducted on 381 consecutive randomly selected elderly people in Rasht during 2017. Data was collected using a questionnaire that included demographic characteristics, common chronic diseases, pattern of drug use, and medication adherence by face-to-face interviewing at the centers covered by the retirement fund. Data analysis was carried out using descriptive statistics and Chi-square tests. Results: Of 381 people, 88.5% took drugs. The average number of drugs used and the self-medication frequency were 3.95 per day, and 35.7%, respectively. The most common causes of self-medication included previous use of the same drug and symptom recovery. The most commonly used drug group among the research groups included lipid-lowering agents (48.8%). Atorvastatin, Aspirin, and Losartan were the most commonly used drugs in the elderly that most of subjects (53.4%) had medium medication adherence. Conclusions: Since the elderly suffer from multiple diseases simultaneously, they often use several drugs. Therefore, selfmedication and also medication adherence are the most important issues in this period. Educational interventions on the proper pattern of drug use among older people seem to be necessary.

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Utilization of potentially inappropriate medications in elderly patients in a tertiary care teaching hospital in India

Cited by 26 publications

References 29 publications

A Prospective Study on inappropriate Drug utilization in Geriatric Patients at A Tertiary Care Teaching Hospital

A Prospective Study on inappropriate Drug utilization in Geriatric Patients at A Tertiary Care Teaching Hospital

The study on prevalence of polypharmacy in elderly patients presenting for first time to the geriatric clinic of a tertiary care hospital in Kerala

Drug Use Pattern Among Elderly People Referred to the Retirement Centers

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