Background Regardless of its benefit in promoting maternal health and the health of her developing fetus, and little is known about preconception care practice in Ethiopia. The purpose of this study, therefore, is to determine the utilization of preconception health care services and its determinants among women following ANC in Private MCH Hospitals in Addis Ababa.Methods A Hospital based cross-sectional study was conducted from April 1 to April 30,2022 among 385 women attending ANC in Private MCH Hospitals. Data were collected by a pretested self-administered semi-structured questionnaire. To identify the determinants associated with the utilization of preconception care bivariable and multivariable logistic regression analysis were performed. Adjusted odds ratios (AOR) with 95% CI were estimated to assess the strength of associations and statistical significance was declared at a p-value < 0.05.Results The utilization of PCC among the pregnant mothers according to our study was 40%. Professional/technical/managerial occupation (AOR = 4.3, 95%CI = 1.13, 16.33), good knowledge on PCC (AOR = 3.5, 95%CI = 1.92, 6.53),having unintended pregnancy (AOR = 0.1, 95%CI = 0.03, 042), history of family planning use before conception (AOR = 3.9, 95%CI = 1.20, 12.60), having pre-existing medical disease(s) (AOR = 8.4, 95%CI = 2.83, 24.74) and having obstetric problem(s) in previous pregnancies (AOR = 3.2, 95%CI = 1.55, 6.50) were significantly associated with preconception care utilization.Conclusions This study found out that the utilization of preconception care in the private MCH Hospitals is still low i.e., only 40%. Occupation, level of knowledge, having intended pregnancy, history of family planning use before conception, having obstetric problem(s) in previous pregnancy and having pre-existing medical condition(s) were independently associated with preconception care utilization. Lack of awareness about the availability of the services and having unintended pregnancy were the main reasons for not utilizing the PCC services.