Utilization of the 1320-nm Nd:YAG Laser for the Reduction of Photoaging of the Hands

Sadick, Neil S.; Schecter, Amy K.

doi:10.1111/j.1524-4725.2004.30341.x

Cited by 25 publications

(22 citation statements)

References 40 publications

(55 reference statements)

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“…The relatively long 1,320-nm wavelength achieves excellent penetration into the papillary and midreticular dermis where it is non-specifically absorbed by dermal water [22]. The large scattering coefficient of the 1,320-nm Nd:YAG laser causes the thermal energy to disperse laterally within the dermis, inducing a large volume of dermal injury relative to the beam size [23]. For the long-pulsed 1,064-nm laser, since the main target is protein with water as a secondary target, the heating effect in the target tissue absorbing the 1,064-nm beam is non-specific [20].…”

Section: Discussionmentioning

confidence: 99%

Laser induced collagen remodeling: A comparative study in vivo on mouse model

et al. 2008

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Background and Objective: Many lasers have claimed the clinical efficacy on skin rejuvenation. In this study, the mechanisms of laser induced collagen remodeling were explored systematically on a Kunming (KM) mouse model in vivo by comparing the different non-ablative laser effects using four different laser treatment modalities. Materials and Methods: The dorsal skin of KM mice was exposed by depilation before the laser treatments. Four laser treatment modalities were used: the 595-nm pulsed dye laser (PDL) (10 ms), 1,320-nm neodymium-yttriumaluminum garnet (Nd:YAG) laser (0.35 ms), 1,064-nm Nd:YAG laser with Q-switched (5 ns), and long-pulsed (0.3 ms) mode. Each modality exposed one side of the mouse dorsal skin leaving the other side as the contralateral control. Then skin histology, fibroblast number, and the genesis of collagen type I and III were studied by comparing the treatment site and control site at 1 hour, 1 day, 1 week, 3 weeks, 4 weeks, and 8 weeks after laser treatment. Hydroxyproline content of the skin tissue was measured 4 weeks and 8 weeks after laser exposure. Results: All laser treatments led to marked improvements in dermal layer thickness and collagen fiber density, and the increase in fibroblast number and hydroxyproline content compared with their own controls. Collagen synthesis and remodeling induced by the Q-switched 1,064-nm laser was most effective 4 weeks after treatment, while there was no significant difference among the other three modalities. Among the new collagen genesis after the different laser treatments, collagen type III increased sharply after the Q-switched 1,064-nm laser treatment whereas more collagen type I was elicited by the other laser treatment modalities. Conclusions: The efficacy of photo-mechanical effects in promoting more effectively the synthesis of collagen type III, whereas the photo-thermal effect favored more the formation of collagen type I.

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Section: Discussionmentioning

confidence: 99%

Laser induced collagen remodeling: A comparative study in vivo on mouse model

et al. 2008

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“…Die geschädigte Haut wird durch Falten, Hauterschlaffung und Pigmentstörungen charakterisiert [21,23] [15]. Auch wenn eine alte Hand problemlos von einer jungen unterschieden werden kann, sind die Kriterien eher vage definiert [4].…”

Section: Alterungsprozessunclassified

“…Unterschiedliche Verfahren wie chemische Peelings, Dermabrasio und ablative oder nichtablative Laserbehandlungen führen alle zu iatrogener Verletzung der Dermis zur Stimulation der Neokollagenese ( [8,21];…”

Section: Minimal-invasive Therapieunclassified

“…Der Anwendungsbereich des Lasers und IPL ist neben Faltenbildung besonders die Behandlung der Altersflecken und anderweitiger Pigmentstörungen [11,21]. Bei Einsatz ablativer Laserbehandlungen kommt es zur Induktion thermaler Schä-den an Epidermis und Dermis, was zur Fibroblastenaktivierung und Neokollagenese führt [16].…”

Section: Laserbehandlung Psr Und Iplunclassified

“…Bei Einsatz ablativer Laserbehandlungen kommt es zur Induktion thermaler Schä-den an Epidermis und Dermis, was zur Fibroblastenaktivierung und Neokollagenese führt [16]. Bei nichtablativer Lasertherapie, PSR-und IPL-Behandlung werden höhere Wellenlängen verwendet, die eine größere Eindringtiefe haben [11,21]. Durch simultane Oberflächenkühlung bleibt die Epidermis intakt, eine schnellere Regeneration ohne epidermale Regeneration wird hierdurch erwartet.…”

Section: Laserbehandlung Psr Und Iplunclassified

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Alterung und ideale Ästhetik der Hand

Jakubietz¹,

Grünert²,

Kloss³

et al. 2009

Hautarzt

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The appearance of the hand is clearly secondary to its function. Nonetheless, aging changes on the hands are of considerable importance to many patients. Although rejuvenation of the hand has attracted increased interest in plastic surgery recently, the dermatologists have dealt with this problem for a longer time. Successful rejuvenation requires thorough analysis of the underlying pathophysiology. Hand aging is characterized by dermal and subcutaneous volume loss resulting wrinkle formation. Aging is also associated with increased visibility of tendons and veins as well as age spots and precancerous lesions. Hand rejuvenation aims at successfully reversing this three-dimensional process. The majority of treatment options address only partial aspects of the aging process. Topical treatments are the mainstay of therapy as these changes are most obvious. As patients will mainly seek advice from dermatologist, this field requires increased attention.

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Non‐Ablative Photorejuvenation and Skin Remodeling

Goldberg

2007

Laser Dermatology

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Utilization of the 1320-nm Nd:YAG Laser for the Reduction of Photoaging of the Hands

Abstract: This case series demonstrates that the 1320-nm Nd:YAG laser with cryogen cooling can be effective for rejuvenation of photoaged hands.

Cited by 25 publications

References 40 publications

Laser induced collagen remodeling: A comparative study in vivo on mouse model

Laser induced collagen remodeling: A comparative study in vivo on mouse model

Alterung und ideale Ästhetik der Hand

Non‐Ablative Photorejuvenation and Skin Remodeling

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