Utilization of Trauma-Related Deaths for Organ and Tissue Harvesting

Kennedy, Alfred P.; West, John C; Kelley, Stephen E.; Brotman, Shari

doi:10.1097/00005373-199210000-00005

Cited by 15 publications

(6 citation statements)

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“…2 Consent rates by ethnicity This deficit is highly relevant to surgical intensivists, as patients sustaining traumatic brain injury are one of the largest segments of the potential donor pool, second only to cerebrovascular accident and stroke [1]. Nevertheless, it is estimated that only 3%-4% of hospital deaths result in a potential organ donor [3,4], and of those, only 12-15% will become actual donors [3,[7][8][9].…”

Section: Discussionmentioning

confidence: 99%

“…Trauma comprises one of the largest segments of potential organ donor pool [1]. Nevertheless, only a small percentage of patients who progress to become potential organ donors proceed to organ donation [3, 4].…”

Section: Introductionmentioning

confidence: 99%

“…Classically, organ procurement failure has largely been attributed to an inability to maintain cardiovascular function long enough for the procurement process to be completed [3, 7, 8]. More recently, refusals of consent by family members has also been identified as a major reason for the failure of organ donation [9].…”

Section: Introductionmentioning

confidence: 99%

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Donor Conversion and Procurement Failure: The Fate of Our Potential Organ Donors

et al. 2010

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Donor Conversion and Procurement Failure: The Fate of Our Potential Organ Donors

et al. 2010

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“…Perceived miscommunication from the health care professionals involved can play a major role in family refusal. 11 For example, a premature request or conflicting statements from a variety of physicians can undermine a family's willingness to consider donation. 11 The Canadian health care system does not yet have a reliable information collection procedure to assess the extent to which Canadian hospitals can identify potential donors, and take the steps to maximize organ use from each donor.…”

Section: Discussionmentioning

confidence: 99%

Potential organ donors referred to Ontario neurosurgical centres

Tenn-Lyn

Doig

Shemie

et al. 2006

Can J Anesth/J Can Anesth

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Purpose: Eleven hospitals in Ontario are adult neurosurgical centres (ONCs). Patients transferred to ONCs from community hospitals with acute intracranial emergencies often have non-survivable injuries, and may be returned to the referring hospital for end-of-life care. These referring hospitals may not be familiar with neurological determination of death, or organ donation. Our objective was to determine the number of patients with severe brain injuries assessed in ONC emergency departments where progression to brain death may be reasonably expected, and to determine their outcome. Methods:A one-year retrospective cohort study was undertaken using a convenience sample of patients transferred to eight ONCs for neurosurgical assessment, with evidence of either (a) brain death in the emergency department, or (b) severe brain injury who met criteria of a reasonable likelihood of progression to brain death. The outcome of these patients to disposition from the ONC was determined by chart review.Results: Three thousand four hundred and forty-seven patients were identified of whom 141 met inclusion criteria. Eleven patients (7.8%) were pronounced dead in the emergency department, 96 (68.1%) patients were admitted, and 34 (24.1%) were transferred back to their referring hospital. Fourteen patients (9.9%) became organ donors: two died in the emergency department and 12 died following admission. Conclusions: A significant number of patients transferred to ONCs have an injury with a likelihood of progressing to brain death, but only a small proportion of these patients become organ donors. Emergency department triage, assessment and admission decisions for patients with intracranial catastrophes should consider diagnostic criteria for brain death and recognition of donor potential as part of end-of-life care. Objectif

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“…Other facilities have demonstrated similar experiences. [55][56][57] With the emergence of more effective noninvasive monitoring modalities to guide fluid resuscitation and vasopressor use, newer technologies may also prove beneficial the resuscitative management of this unique population.…”

Section: Organ Donor Protocols and Studiesmentioning

confidence: 99%

Aggressive Organ Donor Management Protocol

DuBose

Salim

2008

J Intensive Care Med

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As of August 2007, 96 900 people are awaiting organ transplantation in the United States, while only 28 930 transplants were performed in 2006. With such a large gap between organ need and organ availability, it is inevitable that many will die while awaiting transplantation. This organ shortage has become a national public health crisis, and as a response, the United States Department of Health and Human Services launched the Organ Donation Breakthrough Collaborative, an ambitious campaign to dramatically increase the number of transplantable organs. One of the suggested strategies involves maximizing the number of organs obtained from the available cadaveric "brain dead'' donor pool by using donor management protocols that optimize and treat the profound physiological disturbances that are associated with brain death. The use of these standardized and aggressive donor management protocols has been shown to increase the number of transplanted organs and prevent the number of donors lost due to medical failures. A protocol-driven approach by a dedicated organ donor management team should be considered a key component of any program designed to bridge the gap between organ supply and demand.

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Utilization of Trauma-Related Deaths for Organ and Tissue Harvesting

Cited by 15 publications

References 0 publications

Donor Conversion and Procurement Failure: The Fate of Our Potential Organ Donors

Donor Conversion and Procurement Failure: The Fate of Our Potential Organ Donors

Potential organ donors referred to Ontario neurosurgical centres

Aggressive Organ Donor Management Protocol

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