Utlization of rheological parameters for the prediction of β-TCP suspension suitability to fabricate bone tissue engineering scaffold through foam replication method

Saba, Golshan; Hesaraki, Saeed; Hajisafari, Mahmoud

doi:10.1007/s41779-018-0187-2

Cited by 4 publications

(2 citation statements)

References 30 publications

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“…Bioglass-based scaffolds with homogeneous well-defined porous Both slurries showed adequate rheological behavior to impregnate the polymer filaments of the sponge homogeneously. The shearthinning behavior and thixotropic of the slurry used on the first F I G U R E 1 0 Schematic mechanism of silver nanoparticles adhesion to the scaffold impregnation played an important role in the removal of slurry excess impregnated on the sponge (Saba, Hesaraki, & Hajisafari, 2018). The lower viscosity of the slurry used on the second impregnation not closed the preexisted pores.…”

Section: Discussionmentioning

confidence: 99%

Bioglass‐based scaffolds coated with silver nanoparticles: Synthesis, processing and antimicrobial activity

Oliveira

Barbosa

Hurtado

et al. 2020

J Biomedical Materials Res

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Over the past few years, several tridimensional synthetic bone grafts, known as scaffolds, are being developed to overcome the autologous grafts limitations. Among the materials used on the production of scaffolds, the 45S5 bioglass stands out due to its capacity of bonding to hard and soft tissues. Silver nanoparticles are well-known for their antimicrobial properties and their incorporation on the scaffold may promote its antimicrobial response, avoiding microorganism proliferation on the materials surface. This study proposes a simple way to coat 45S5 bioglass-based scaffolds with silver nanoparticles. The scaffolds were obtained by the sponge replication technique and the silver nanoparticles were incorporated by soaking under ultrasonic stirring. The antimicrobial activity of the scaffolds was analyzed against three different microbial strains: S. aureus, P. aeruginosa, and C. albicans. Due to the heat treatment during the scaffold production, the bioglass crystalized mainly in a sodium calcium silicate phase, forming a glass-ceramic scaffold. The silver nanoparticles were coated in a welldistributed manner throughout the scaffold, while avoiding their aggregation. The coated scaffold inhibited the growth of all the analyzed microorganism. Therefore, the use of ultrasonic stirring to coat the bioglass scaffold with silver nanoparticles showed to be an efficient way to promote its antimicrobial response.

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Section: Discussionmentioning

confidence: 99%

Bioglass‐based scaffolds coated with silver nanoparticles: Synthesis, processing and antimicrobial activity

Oliveira

Barbosa

Hurtado

et al. 2020

J Biomedical Materials Res

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“…The pore size, porosity and compressive strength of pure, binary and ternary doped CHA scaffolds are presented in Table 3. Overall, the average pore sizes of different sintered scaffolds are in the range of 327-428 μm, which is appropriate for cells penetration, diffusion of nutrients and oxygen as well as removal of waste and carbon dioxide through the blood vessel (200-500 μm) [39]. The ideal pore size is one of a crucial characteristics in order to ensure the cells survival, particularly in the core of the scaffolds upon culture.…”

Section: Scaffold Characterizationmentioning

confidence: 99%

Influence of ternary divalent cations (Mg2+, Co2+, Sr2+) substitution on the physicochemical, mechanical and biological properties of carbonated hydroxyapatite scaffolds

B.I.

M.N.

et al. 2021

J Aust Ceram Soc

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Substitution of ionic either anion or cation in a controlled amount into carbonated hydroxyapatite (CHA) structure is one of the efficient and safest ways in enhancing the properties of the materials. However, most of the works studied only focused on the physical and mechanical properties of single ionic substitution. For the first time, the influence of simultaneous ternary substitutions of divalent cations into porous CHA scaffolds on the physicochemical, mechanical, degradation and in vitro biological properties are investigated in the present study. Three different compositions of porous scaffolds with binary and ternary divalent cations, namely, pure CHA (S11), CoSr CHA (S21) and MgCoSr CHA (S31) were fabricated using polyurethane (PU) foam replication technique. Despite a small amount of Mg 2+ , Co 2+ and Sr 2+ added, these divalent cations had successfully substituted into the Ca 2+ site and remained as single phase B-type CHA. The produced scaffolds demonstrated open, interconnected and uniform pores. Interestingly, simultaneous ternary divalent cations substitution into CHA structure had successfully enhanced the compressive strength of the sintered scaffolds, also promoted better cell attachment and activities than the binary dopedand pure CHA scaffolds. It is important to note that the right choice of divalent cation can be the determining factor in tuning the physicochemical, mechanical and biological properties of CHA scaffolds.

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Rheological insights on Carboxymethyl cellulose hydrogels

Enoch,

Somasundaram

2023

International Journal of Biological Macromolecules

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Utlization of rheological parameters for the prediction of β-TCP suspension suitability to fabricate bone tissue engineering scaffold through foam replication method

Cited by 4 publications

References 30 publications

Bioglass‐based scaffolds coated with silver nanoparticles: Synthesis, processing and antimicrobial activity

Bioglass‐based scaffolds coated with silver nanoparticles: Synthesis, processing and antimicrobial activity

Influence of ternary divalent cations (Mg2+, Co2+, Sr2+) substitution on the physicochemical, mechanical and biological properties of carbonated hydroxyapatite scaffolds

Rheological insights on Carboxymethyl cellulose hydrogels

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