Utredning av autismespekterforstyrrelser i BUP – hvor godt samsvar er det mellom instrumenter og endelig klinisk diagnose?

Berntsen, Hans Jørgen; Ørbeck, Beate; Øvergaard, Kristin Romvig

doi:10.52734/n27qu88p

Cited by 3 publications

(3 citation statements)

References 28 publications

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“…The Norwegian translation of the Wechsler Abbreviated Scale of Intelligence (WASI) was used to assess general intellectual abilities at baseline. This test contains 4 subtests and gives reliable estimates of both full-scale verbal and performance IQ, within less than 1 SD from the more elaborate WAIS-III (Wechsler Adult Intelligence Scale-third edition) estimates [ 26 ].…”

Section: Methodsmentioning

confidence: 99%

Mobile Assessments of Mood, Cognition, Smartphone-Based Sensor Activity, and Variability in Craving and Substance Use in Patients With Substance Use Disorders in Norway: Prospective Observational Feasibility Study

Lauvsnes¹,

Hansen²,

Ankill³

et al. 2023

JMIR Form Res

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Background Patients with substance use disorders (SUDs) are at increased risk for symptom deterioration following treatment, with up to 60% resuming substance use within the first year posttreatment. Substance use craving together with cognitive and mental health variables play important roles in the understanding of the trajectories from abstinence to substance use. Objective This prospective observational feasibility study aims to improve our understanding of specific profiles of variables explaining SUD symptom deterioration, in particular, how individual variability in mental health, cognitive functioning, and smartphone use is associated with craving and substance use in a young adult clinical population. Methods In this pilot study, 26 patients with SUDs were included at about 2 weeks prior to discharge from inpatient SUD treatment from 3 different treatment facilities in Norway. Patients underwent baseline neuropsychological and mental health assessments; they were equipped with smartwatches and they downloaded an app for mobile sensor data collection in their smartphones. Every 2 days for up to 8 weeks, the patients were administered mobile ecological momentary assessments (EMAs) to evaluate substance use, craving, mental health, cognition, and a mobile Go/NoGo performance task. Repeated EMAs as well as the smartphone’s battery use data were averaged across all days per individual and used as candidate input variables together with the baseline measures in models of craving intensity and the occurrence of any substance use episodes. Results A total of 455 momentary assessments were completed out of a potential maximum of 728 assessments. Using EMA and baseline data as candidate input variables and craving and substance use as responses, model selection identified mean craving intensity as the most important predictor of having one or more substance use episodes and with variabilities in self-reported impulsivity, mental health, and battery use as significant explanatory variables of craving intensity. Conclusions This prospective observational feasibility study adds novelty by collecting high-intensity data for a considerable period of time, including mental health data, mobile cognitive assessments, and mobile sensor data. Our study also contributes to our knowledge about a clinical population with the most severe SUD presentations in a vulnerable period during and after discharge from inpatient treatment. We confirmed the importance of variability in cognitive function and mood in explaining variability in craving and that smartphone usage may possibly add to this understanding. Further, we found that craving intensity is an important explanatory variable in understanding substance use episodes.

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Section: Methodsmentioning

confidence: 99%

Mobile Assessments of Mood, Cognition, Smartphone-Based Sensor Activity, and Variability in Craving and Substance Use in Patients With Substance Use Disorders in Norway: Prospective Observational Feasibility Study

Lauvsnes¹,

Hansen²,

Ankill³

et al. 2023

JMIR Form Res

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“…Høyere skårer på 3Di indikerer økende avvik. Vi har ikke funnet andre norske 3Di-studier utover vår egen hvor vi fant akseptabel verdi for hvor nøyaktig 3Di var til å skille mellom barn med og uten klinisk ASF-diagnose i BUP (sensitivitet/spesifisitet > 70 %) (Berntsen et al, 2021). ADOS-2 er en revidert utgave av et standardisert, semi-strukturert intervju og en adferdsobservasjon av barn og unge for å vurdere ASF.…”

Section: Målunclassified

Hvor nøyaktig identifiserer screeninginstrumentet Social Communication Questionnaire autismespekterforstyrrelser i BUP?

Ørbeck¹,

Berntsen²,

Øvergaard³

2022

TNPF

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Background: The accuracy of the Norwegian Social Communication Questionnaire (SCQ) in identifying autism spectrum disorder (ASD) within child psychiatry is not known. Method: We investigated the accuracy of SCQ in identifying clinically diagnosed ASD and ASD classified by the Developmental, Dimensional and Diagnostic Interview (3Di) and the Autism Diagnostic Observation Schedule (ADOS-2). Results: The SCQ cut-off of 15 showed low sensitivity (Se) for correct classification of clinically diagnosed ASD (Se = 38%) and ADOS-2 classified ASD (Se = 30%) with 78% and 76% specificity (SP), respectively. For 3Di classified ASD, Se was somewhat higher (49%) and had good specificity (86%), with the best positive predictive value (.73). Conclusions/Implications: The SCQ showed low accuracy in identifying a clinical ASD diagnosis in child psychiatry. However, children with SCQ scores at or above threshold had a high risk of also being categorised with ASD according to the 3Di. We recommend that future studies include more detailed information about the basis for the final diagnostic conclusions. Furthermore, SCQ's characteristics should be evaluated in samples of children within a broad range of ASD that includes individuals with delayed development. Investigation of the suitability of other screening instruments for ASD for diagnostic work in child psychiatric clinics is also needed. Keywords: Autism Diagnostic Observation Schedule (ADOS-2), Developmental, Dimensional and Diagnostic Interview (3Di), sensitivity; specificity, Social Communication Questionnaire (SCQ)

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“…Høyere skårer på 3Di indikerer økende avvik. Vi har ikke funnet andre norske 3Distudier utover vår egen hvor vi fant akseptabel verdi for hvor nøyaktig 3Di var til å skille mellom barn med og uten klinisk ASF-diagnose i BUP (sensitivitet/spesifisitet > 70 %) (Berntsen et al, 2021).…”

Section: Målunclassified

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2022

TNPF

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Utredning av autismespekterforstyrrelser i BUP – hvor godt samsvar er det mellom instrumenter og endelig klinisk diagnose?

Cited by 3 publications

References 28 publications

Mobile Assessments of Mood, Cognition, Smartphone-Based Sensor Activity, and Variability in Craving and Substance Use in Patients With Substance Use Disorders in Norway: Prospective Observational Feasibility Study

Mobile Assessments of Mood, Cognition, Smartphone-Based Sensor Activity, and Variability in Craving and Substance Use in Patients With Substance Use Disorders in Norway: Prospective Observational Feasibility Study

Hvor nøyaktig identifiserer screeninginstrumentet Social Communication Questionnaire autismespekterforstyrrelser i BUP?

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