UV‐Blocking and Light‐Responsive Poly (ϵ‐Caprolactone)/ZIF‐8 Multifunctional Composite Films for Efficient Antibacterial Activities

Abstract

Antibacterial photodynamic therapy (APDT) has received considerable attention owing to its superiority. ZIF-8 was used to address the poor stability of the photosensitizer Rose Bengal (RB) encapsulation to synthesize RB@ZIF-8 NPs, which were doped into a composite film with poly (ɛcaprolactone) (PCL) and polyvinyl alcohol-quaternary ammonium chitosan (PVA-QCS) as substrates to form composite films (PQZ). The composite films exhibited excellent photodynamic sterilization and good resistance to bacterial adhesion. The tensile strength of the film increased to 43.4 MPa, which was approximately 1.8 times that of the PCL film. With the addition of SiO 2 and RB@ZIF-8 NPs, the film exhibited water repellency and UV-blocking properties. RAW264.7 cells were selected using the MTT method to confirm that the composite films had excellent biocompatibility and had no significant inhibitory effect on cell growth and reproduction. PQZ multifunctional composite films show potential as novel APDT antimicrobial materials for food packaging.

Microfluidic Spinning of Metal–Organic Framework-Loaded Nanofibers toward High-Efficient Particulate Matter Removal and Antibacterial Filters

“…aureus, the corresponding inhibition rates were 77, 77, 15, 100, 94, and 100%, respectively. Notably, the PCL/ZIF-8@CCM shows a lower inhibition rate, which might be attributed to the bacterial adsorption and nonantibacterial feature of pure PCL. , These results indicate that the loading of ZIF-8@CCM endows the fiber membranes with a higher antibacterial activity. With both excellent PM removal performances and antibacterial activity, the ZIF-8@CCM-loaded fiber membrane provides an ideal fibrous filter.…”

ZIF-8-Modified Black Phosphorus Nanosheets Incorporated into Injectable Dual-Component Hydrogels for Enhanced Photothermal Antibacterial and Osteogenic Activities

“…21 ZIF-8 reportedly exhibits high antibacterial and anti-inflammatory activities and pH sensitivity that enhance its antibacterial efficacy within acidic infectious microenvironments. 22,23 Therefore, ZIF-8-stabilized BPNs may be a win−win strategy for antimicrobial and antiinflammatory PTT and promoting bone regeneration. However, whether this strategy is feasible remains unknown.…”

“…ZIF-8 possesses the advantages of MOFs with high porosity, specific surface, and stability, making them highly sought after in biomedical applications such as imaging and drug delivery . ZIF-8 reportedly exhibits high antibacterial and anti-inflammatory activities and pH sensitivity that enhance its antibacterial efficacy within acidic infectious microenvironments. , Therefore, ZIF-8-stabilized BPNs may be a win–win strategy for antimicrobial and anti-inflammatory PTT and promoting bone regeneration. However, whether this strategy is feasible remains unknown.…”