UV hardening therapy: A novel intervention in patients with photosensitive cutaneous lupus erythematosus

Photosensitivity testing in children

“…Radiation sources and their emission spectrum, filters, the UV intensity measuring, and calibration have been described previously. [6][7][8][9]13,14 The final diagnosis of a photosensitivity disorder was based on both the clinical features and the phototest results.…”

“…6,7 This included 5 children with PLE, 3 children with PhAD, one child with an ambiguous photosensitivity (PLE and PhAD), and one child with AP. Because of the retrospective nature of our study it was not possible to evaluate the effect of this therapy.…”

“…Phototests can also determine the specific eliciting wavelengths for the photodermatosis, [6][7][8][9] establish the extent of photosensitivity, evaluate the effects of treatment, and monitor the photosensitivity over time. [10][11][12] Abbreviations used: Descriptions of phototesting procedures in children are scarce and limited.…”

Current and future treatment options for cutaneous lupus erythematosus

“…Longer-wavelength UVA1 (340 --400 nm) seems less likely to flare the disease and may even be beneficial. Several small trials using low-dose UVA1 (6 --12 J/cm 2 ) have demonstrated benefit in systemic symptoms of SLE [58,59]. There are no published trials using UVA-1 specifically for CLE.…”

Cutaneous lupus erythematosus: Update of therapeutic options

“…In a retrospective study of continuous, homebased, UVB hardening therapy, 44 patients with confirmed photosensitivity and cutaneous manifestations of LE were included (9 SLE, 21 DLE, 10 SCLE, 4 not-specified CLE). 58 Exposure to the UVB source was performed year-round, 3 times weekly with increasing doses. In all, 35 patients were able to gradually increase their monthly UVB dose and maintained their increased UVB tolerance over longer periods of time.…”