UV-O3-treated and protein-coated polymer surfaces facilitate endothelial cell adhesion and proliferation mediated by the PKCα/ERK/cPLA2 pathway

Surface immobilization of fibronectin-derived PHSRN peptide on functionalized polymer films – Effects on fibroblast spreading

“…2b) samples, respectively. It is evident that UV-O 3 treatments induced the formation of C(@O)O À species (at about 289.0 ± 0.2 eV), in addition to the increase of the amount of C-O-C species (at about 286.4 ± 0.2 eV) already present on the HYB surfaces [30,32]. Accordingly, the oxygen content onto the HYL surfaces increased compared to the HYB ones, the stoichiometry changes from AFM measurements indicated that UV-O 3 treatment did not noticeably affect the smoothness of the polymer, and so the increased water wettability of the surface-modified films is entirely due to the formation of polar groups and not influenced by changes of surface roughness [38].…”

“…In the present work we adopted the strategy of triggering the spontaneous adsorption process of the cell-adhesive PHSRN peptide by simply modifying the surface free energy properties of the substrate [30][31][32]. In particular, we investigated the PHSRN adsorption process onto hydrophobic/hydrophilic polysiloxane surfaces as well as the surface chemical structure and topography of the peptide adlayers.…”

Assessing the Suitability of Electrospun Poly(Ethylene Terephthalate) and Polystyrene as Cell Carrier Substrates for Potential Subsequent Implantation as a Synthetic Bruch's Membrane

“…PET has been investigated as a material for cell transplantation [20] and has been electrospun to form fibrous scaffolds for large vascular replacements due to its biostability [21]. UV=ozone treatment has also been investigated for PET films [22].…”

Surface modification of implanted cardiovascular metal stents: From antithrombosis and antirestenosis to endothelialization

“…Physical surface modifications, including the microtopography and nanotopography of the metal surface and fluid shear stress can promote endothelialization in vitro . Some researchers also have planted ECs in vitro onto surfaces that were modified, such as ultraviolet‐ozone irradiation magnetron sputtering, PIII and deposition, or immobilized VEGF . Nevertheless, in vivo tests are required, and the issues of maintaining rapid endothelialization, firm EC adhesion and upholding normal EC function still remain.…”