UV/ozone modification of poly(dimethylsiloxane) microfluidic channels

Berdichevsky, Yevgeny; Khandurina, Julia; Guttman, András; Lo, Yu‐Hwa

doi:10.1016/j.snb.2003.09.022

Cited by 280 publications

(241 citation statements)

References 24 publications

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“…While this plasma treatment process is incompatible with hydrogels already present on the PDMS due to vacuum requirements, a UV-Ozone treatment may be substituted to achieve the same effect at a slower rate while maintaining hydrogel integrity [59] . After subsequent hydrogel and PDMS layers were printed, the device was exposed to the flood UV lamp.…”

Section: Methodsmentioning

confidence: 99%

3D Printing of Transparent and Conductive Heterogeneous Hydrogel–Elastomer Systems

et al. 2017

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A hydrogel–dielectric‐elastomer system, polyacrylamide and poly(dimethylsiloxane) (PDMS), is adapted for extrusion printing for integrated device fabrication. A lithium‐chloride‐containing hydrogel printing ink is developed and printed onto treated PDMS with no visible signs of delamination and geometrically scaling resistance under moderate uniaxial tension and fatigue. A variety of designs are demonstrated, including a resistive strain gauge and an ionic cable.

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Section: Methodsmentioning

confidence: 99%

3D Printing of Transparent and Conductive Heterogeneous Hydrogel–Elastomer Systems

et al. 2017

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“…An interesting tree-shaped structure was attempted to separate peptides in CEC mode [52]. Plasma-mediated glassification reportedly makes PDMS channel surfaces uniform [53]. Among a few disadvantages of PDMS are poorly defined EOF and adsorption of nonpolar hydrophobic samples [54][55][56].…”

Section: Pdms Microchipsmentioning

confidence: 99%

New advances in microchip fabrication for electrochromatography

Szekeres

Guttman

2005

Electrophoresis

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There is a great demand in separation technologies for faster and more effective analysis processes. Miniaturization is a suitable technique for satisfying this demand as reduction in size gives increased separation speed with higher efficiency. CEC is an electric-field-mediated separation technique where the liquid flow is generated by the electric field itself. The main advantage of using electric field over pressure for flow generation is the flat flow profile of the EOF; thus, CEC is one of the best candidates to construct a novel and high-efficiency microanalytical device. The aim of the present paper is to review the basic fabrication and bonding principles, as well as connection and system integration options for microfluidics-based electrochromatography. The physical structure and fluidic channel formation are critically evaluated, including glass microstructuring and fusion bonding. Recent developments in nanoflow measurements and the application of various flow control units are also extensively discussed.

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“…The surface modification (or derivatization) of PDMS is normally achieved through the physical modification of the PDMS surface via plasma treatment or etching [13][14][15] or via the chemical derivatization of the surface with or without prior activation. Chemical modification relies on three primary methodologies for attaching a patent layer of alterant to the device surface: covalent attachment, [16][17][18] polymer grafting, [19][20][21][22] or matrix infiltration/chemisorption.…”

Section: Introductionmentioning

confidence: 99%

Droplet confinement and leakage: Causes, underlying effects, and amelioration strategies

2015

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The applicability of droplet-based microfluidic systems to many research fields stems from the fact that droplets are generally considered individual and selfcontained reaction vessels. This study demonstrates that, more often than not, the integrity of droplets is not complete, and depends on a range of factors including surfactant type and concentration, the micro-channel surface, droplet storage conditions, and the flow rates used to form and process droplets. Herein, a model microfluidic device is used for droplet generation and storage to allow the comparative study of forty-four different oil/surfactant conditions. Assessment of droplet stability under these conditions suggests a diversity of different droplet failure modes. These failure modes have been classified into families depending on the underlying effect, with both numerical and qualitative models being used to describe the causative effect and to provide practical solutions for droplet failure amelioration in microfluidic systems. V C 2015 AIP Publishing LLC.

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UV/ozone modification of poly(dimethylsiloxane) microfluidic channels

Cited by 280 publications

References 24 publications

3D Printing of Transparent and Conductive Heterogeneous Hydrogel–Elastomer Systems

3D Printing of Transparent and Conductive Heterogeneous Hydrogel–Elastomer Systems

New advances in microchip fabrication for electrochromatography

Droplet confinement and leakage: Causes, underlying effects, and amelioration strategies

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