Vaccination and SIDS: information from the South Australian SIDS Database

Byard, Roger W.; Mackenzie, Jeanne; Beal, Susan

doi:10.5694/j.1326-5377.1995.tb124675.x

Cited by 4 publications

(3 citation statements)

References 4 publications

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“…Several systematic studies failed to find an association between SIDS and vaccinations. [28][29][30][31][32] The Institute of Medicine recently reviewed sudden unexpected infant deaths, finding that the weight of evidence does not support causal linkage between SIDS and multiple vaccinations routinely scheduled together. 33 Most or all of the GI symptoms reported with PCV might not relate to vaccination, despite positive rechallenges, since diarrhea and vomiting are so prevalent during infancy.…”

Section: Commentmentioning

confidence: 99%

Postlicensure Safety Surveillance for 7-Valent Pneumococcal Conjugate Vaccine

Wise

Iskander²,

Pratt³

et al. 2004

JAMA

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Context Clinical trials evaluate a vaccine's safety before approval, but some risks may escape detection or adequate characterization until larger population exposures occur after licensure. Objective To summarize reports of events occurring after vaccination with 7-valent pneumococcal conjugate vaccine (PCV), including those that may warrant further investigation to assess possible causation by PCV. Design Descriptive epidemiology of reports submitted to the Vaccine Adverse Event Reporting System (VAERS), a national passive surveillance database. Setting and Patients United States during first 2 years after licensure of PCV (February 2000 through February 2002). Reports studied were for children younger than 18 years and vaccinated with PCV. Main Outcome Measures Numbers and proportional distributions of reports. Results A total of 4154 reports of events following PCV were submitted to VAERS, for a rate of 13.2 reports per 100000 doses distributed. Multiple vaccines were given in 74.3% of reports.The most frequently reported symptoms and signs included fever, injection site reactions, fussiness, rashes, and urticaria. Serious events were described in 14.6% of reports. There were 117 deaths, 23 reports of positive rechallenges, and 34 cases of invasive pneumococcal infections possibly representing vaccine failure. Immune-mediated events occurred in 31.3% of reports. All 14 patients with anaphylactic or anaphylactoid reactions survived. Thrombocytopenia developed in 14 patients and serum sickness in 6 others. Neurologic symptoms occurred in 38% of reports. Seizures described in 393 reports included 94 febrile seizures. Conclusions The majority of reports to VAERS in the first 2 years after licensure of PCV described generally minor adverse events previously identified in clinical trials. The proportion of reports portraying serious events was similar to that for other vaccines. Although there are important limitations in passive surveillance data, and caution in their interpretation is necessary, symptoms experienced by a few children more than once after successive PCV doses, including allergic reactions, prolonged or abnormal crying, fussiness, dyspnea, and gastrointestinal distress, warrant continued surveillance, as do reports of rare but potentially serious events, such as seizures, anaphylactic or anaphylactoid reactions, serum sickness, and thrombocytopenia.

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Section: Commentmentioning

confidence: 99%

Postlicensure Safety Surveillance for 7-Valent Pneumococcal Conjugate Vaccine

Wise

Iskander²,

Pratt³

et al. 2004

JAMA

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“…Additionally, the coverage of vaccines in relation to SIDS from 1984 to 2004 has been inconsistent in Canadian newspapers. Several studies have shown immunization does not increase the risk of SIDS and may even be protective against SIDS (Byard et al, 1995;Essery et al, 1999;Fleming et al, 2001;Jonville-Bera et al, 1995;Mitchell et al, 1995). The inconsistency in the coverage of vaccines is problematic and has the potential to deter parents from immunizing their infants.…”

Section: Reporting Of Sids Preventionmentioning

confidence: 99%

Analysis of sudden infant death syndrome coverage in Canadian newspapers

Ahmed

Mitchell

Wolbring

2018

J Child Health Care

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Sudden infant death syndrome (SIDS; also known as crib death) describes the sudden unexpected death of an infant under one year of age, which remains unexplained after a thorough investigation. SIDS is a public health concern. It is the fourth leading cause of infant death in Canada. Newspapers are a major source of health information for the public, shape public perceptions and can direct the discussion around issues. Despite the potential influence of newspapers, no study has examined the portrayal of SIDS in Canadian newspapers over time. The purpose of our study was to gain an understanding of SIDS coverage in Canadian English language newspapers using the Canadian Newsstream database from 1970 to 2015 and the historical database: The Globe and Mail from 1844 to 1977. Generating descriptive quantitative and qualitative data, we noted a decline in SIDS coverage over time. Blame and misdiagnosis were two dominant themes in the coverage of SIDS with many other aspects around SIDS missing; for example, indigenous people, who are at higher risk for SIDS, were rarely mentioned. Our findings suggest problems in the content and frequency of coverage of SIDS that have the potential to shape the public understanding of SIDS.

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“…SIDS deaths occur during the age range when many vaccinations are given and thus you would expect vaccinations to precede SIDS simply by chance. However, several well‐designed studies have shown that immunization does not increase the risk of SIDS and may even lower the risk 31−35 . Conversely, other factors such as prone sleeping position, maternal smoking, soft bedding, infections, bottle feeding and low birthweight have been clearly shown to be associated with SIDS 36 .…”

Section: Vaccines and Sudden Infant Death Syndromementioning

confidence: 99%

Immunization myths and realities: Responding to arguments against immunization

MacIntyre

Leask

2003

J Paediatrics Child Health

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As vaccination programs continue to successfully control more and more infectious diseases, and the effects of these diseases become less visible, there has been increased focus on adverse events following immunization. Vaccines have been falsely implicated in the causation of a range of conditions, especially those which affect infants and young children, and whose aetiology is unknown, poorly understood or multifactorial. This paper explores some of the common immunization myths that clinicians may face. It is essential that health professionals have access to accurate information and are able to respond appropriately to parental concerns. This involves good communication; listening, empathy and tailoring advice to the specific concerns of the parent. Finally, health professionals need to provide consistent messages based on solid research evidence.

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Vaccination and SIDS: information from the South Australian SIDS Database

Cited by 4 publications

References 4 publications

Postlicensure Safety Surveillance for 7-Valent Pneumococcal Conjugate Vaccine

Postlicensure Safety Surveillance for 7-Valent Pneumococcal Conjugate Vaccine

Analysis of sudden infant death syndrome coverage in Canadian newspapers

Immunization myths and realities: Responding to arguments against immunization

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