The review presents the recommendations of the American College of Rheumatology on vaccination of patients with rheumatic diseases. The indications for vaccination against major infections and the tactics of immunization with inactivated vaccines are highlighted. The possibility of safe vaccination with any disease activity and simultaneous administration of several vaccines is emphasized. The conditions of immunization with live attenuated vaccines are considered. The principles of vaccination of children born to mothers treated with biological drugs, as well as recommendations for the contacts of rheumatological patients with vaccinated population are reflected. Emphasis is placed on the need for joint decision-making by the rheumatologist and the patient.