Vaccination of haemopoietic stem cell transplant recipients: guidelines of the 2017 European Conference on Infections in Leukaemia (ECIL 7)

Cordonnier, Catherine; Einarsdottir, Sigrun; Cesaro, Simone; Blasi, Roberta Di; Mikulska, Małgorzata; Rieger, Christina; Lavallade, Hugues de; Gallo, Giuseppe; Lehrnbecher, Thomas; Engelhard, Dan; Ljungman, Per

doi:10.1016/s1473-3099(18)30600-5

Cited by 257 publications

(271 citation statements)

References 136 publications

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“…Thus, we strongly recommend not to implement additional antimicrobial prophylaxis on top of recent recommendations by current guidelines concerning the use of antibiotics and G-CSF [16][17][18]. In contrast, vaccination against influenza and especially pneumococci should be recommended for all cancer patients as per current guidelines [19,20].…”

Section: Specific Aspects For Hematologists and Oncologistsmentioning

confidence: 99%

Frequently asked questions regarding SARS-CoV-2 in cancer patients—recommendations for clinicians caring for patients with malignant diseases

et al. 2020

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Since early 2020, the SARS-CoV-2 pandemic has a massive impact on health care systems worldwide. Patients with malignant diseases are assumed to be at increased risk for a worse outcome of SARS-CoV-2 infection, and therefore, guidance regarding prevention and management of the infection as well as safe administration of cancer-therapy is required. Here, we provide recommendations for the management of patients with malignant disease in the times of COVID-19. These recommendations were prepared by an international panel of experts and then consented by the EHA Scientific Working Group on Infection in Hematology. The primary aim is to enable clinicians to provide optimal cancer care as safely as possible, since the most important protection for patients with malignant disease is the best-possible control of the underlying disease.

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Section: Specific Aspects For Hematologists and Oncologistsmentioning

confidence: 99%

Frequently asked questions regarding SARS-CoV-2 in cancer patients—recommendations for clinicians caring for patients with malignant diseases

et al. 2020

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“…The European Conference on Infections in Leukemia recently published 2017 guidelines on vaccination of HSCT recipients. 118 Despite attempts to simplify vaccination protocols for post-HSCT patients, studies have shown gaps in implementation of these schedules with many patients not completing recommended vaccine doses post-HSCT. [119][120][121] Before stem cell donation, donors should receive vaccines that are recommended for them based on their age, risk factors, and exposure history.…”

Section: Malignancy and Chemotherapymentioning

confidence: 99%

Immunization Strategies to Span the Spectrum of Immunocompromised Adults

Whitaker

2020

Mayo Clinic Proceedings

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The Advisory Committee on Immunization Practices to the US Centers for Disease Control and Prevention provides annual recommendations for routine adult immunizations. Many recommendations consider patient factors such as age, medical conditions, and medications that increase an individual's risk for infection with a vaccine-preventable disease. These factors, particularly those that lead to immunocompromise, may also alter the risk-benefit ratio for live vaccines, and/or lead to decreased vaccine immunogenicity and effectiveness. The provider may need to consider alternative vaccination strategies, including higher antigen dose vaccines, adjuvanted vaccines, avoidance of live vaccines, and careful timing of vaccination to optimize safety and effectiveness in immunocompromised populations. This thematic review discusses general principles regarding immunization of adults across the spectrum of immunocompromise, examines current guidelines and studies that support them, and outlines future research needs.

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“…We thank Laura Sticchi and colleagues 1 for their pertinent comments on the 2017 European Conference on Infections in Leukaemia (ECIL 7) vaccination guidelines for patients with haematological diseases, including haematopoietic stemcell transplant (HSCT) recipients. 2,3 We answer their comments about antibody assessment below and address all other issues in the appendix.…”

Section: Ecil 7 Vaccine Guidelinesmentioning

confidence: 99%

“…Syringes had been used multiple times by someone impersonating a doctor. 2 The Pakistani Government, in collaboration with the UN, has taken some appreciable steps towards HIV prevention, such as ensuring the availability of treatment for patients and aiding specialised HIV investigations, but importantly prevention is also linked to awareness in the general population. Nationallevel awareness campaigns, public speaking regarding risks factors, and frequent screening camps should be organised, particularly in remote areas, to aid early detection of index cases, thereby preventing further epidemics.…”

Section: Ecil 7 Vaccine Guidelinesmentioning

confidence: 99%