Vaccine Hesitancy among Parents and Its Association with the Uptake of Measles Vaccine in Urban Settings in Khartoum State, Sudan

Sabahelzain, Majdi M.; Moukhyer, Mohamed; Borne, Bart van den; Bosma, Hans

doi:10.3390/vaccines10020205

Cited by 17 publications

(8 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Patterns of increasing pro-poor inequality in child immunization across some LMICs have been reported in the literature before [ 14 , 16 ]. The emergence of vaccine hesitancy, which is usually observed in more economically developed countries [ 59 , 60 ], could explain this phenomenon [ 61 ]. Various factors may influence vaccine hesitancy, such as parents’ perception of the risks and benefits of child immunization.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Essential childhood immunization in 43 low- and middle-income countries: Analysis of spatial trends and socioeconomic inequalities in vaccine coverage

et al. 2023

View full text Add to dashboard Cite

Background Globally, access to life-saving vaccines has improved considerably in the past 5 decades. However, progress has started to slow down and even reverse in recent years. Understanding subnational heterogeneities in essential child immunization will be critical for closing the global vaccination gap. Methods and findings We use vaccination information for over 220,000 children across 1,366 administrative regions in 43 low- and middle-income countries (LMICs) from the most recent Demographic and Health Surveys. We estimate essential immunization coverage at the national and subnational levels and quantify socioeconomic inequalities in such coverage using adjusted concentration indices. Within- and between-country variations are summarized via the Theil index. We use local indicator of spatial association (LISA) statistics to identify clusters of administrative regions with high or low values. Finally, we estimate the number of missed vaccinations among children aged 15 to 35 months across all 43 countries and the types of vaccines most often missed. We show that national-level vaccination rates can conceal wide subnational heterogeneities. Large gaps in child immunization are found across West and Central Africa and in South Asia, particularly in regions of Angola, Chad, Nigeria, Guinea, and Afghanistan, where less than 10% of children are fully immunized. Furthermore, children living in these countries consistently lack all 4 basic vaccines included in the WHO’s recommended schedule for young children. Across most countries, children from poorer households are less likely to be fully immunized. The main limitations include subnational estimates based on large administrative divisions for some countries and different periods of survey data collection. Conclusions The identified heterogeneities in essential childhood immunization, especially given that some regions consistently are underserved for all basic vaccines, can be used to inform the design and implementation of localized intervention programs aimed at eliminating child suffering and deaths from existing and novel vaccine-preventable diseases.

show abstract

Section: Discussionmentioning

confidence: 99%

“…explain this phenomenon [61]. Various factors may influence vaccine hesitancy, such as parents' perception of the risks and benefits of child immunization.…”

Section: Plos Medicinementioning

confidence: 99%

Essential childhood immunization in 43 low- and middle-income countries: Analysis of spatial trends and socioeconomic inequalities in vaccine coverage

et al. 2023

View full text Add to dashboard Cite

show abstract

“…This study is part of a large research project about measles vaccine hesitancy in Sudan [ 21 , 22 ]. The sample size was calculated for the whole research using a power analysis for the association between measles vaccine hesitancy and the measles vaccination status (outcome), which showed that at least 386 participants were needed to yield an 80% power to detect an odds ratio of 1.7 at alpha level (5%).…”

Section: Methodsmentioning

confidence: 99%

“…Previous studies in Sudan showed the existence of measles vaccine hesitancy is attributed to different drivers including vaccination access-related issues, such as the parental perception that measles vaccination services are unavailable and inaccessible [ 7 , 21 ]. Additionally, a study found that the uptake of the measles vaccine among children is predicted by their parental hesitancy toward the measles vaccine [ 22 ].…”

Section: Introductionmentioning

confidence: 99%

Perceived Vaccine Availability and the Uptake of Measles Vaccine in Sudan: The Mediating Role of Vaccination Hesitancy

et al. 2022

View full text Add to dashboard Cite

This study aimed to evaluate whether measles vaccine uptake can be predicted directly or indirectly by parental perceptions about the availability of measles vaccine services with parental hesitancy towards the measles vaccine as a potential mediator. This was a community-based cross-sectional study conducted at Omdurman locality in Khartoum state, Sudan in February 2019. The study population included parents/guardians having at least one child aged 2–3 years old. Mediation analysis was conducted using two models, the ordinary least squares path analysis and multiple logistic regression. These models considered perceived vaccine accessibility and availability as independent factors, vaccine uptake as dependent factors, and vaccine hesitancy (PACV scores) as a mediator. A total of 495 responded and the mean age of the mothers who participated in the study was 31.1 (SD = 5.73). Half of the respondents (50.1%) completed university education and nearly three-quarters of the respondents (74.7%) were housewives. After controlling for the other factors, including the mother’s age and the number of children, parental perception about the accessibility and availability of the measles vaccine influences the uptake of the measles vaccine indirectly through the mediation effect of measles vaccine hesitancy. We suggest that intervening in measles vaccine hesitancy in addition to measles vaccination access issues will have a positive impact on the uptake and coverage of the measles vaccine in Sudan.

show abstract

“…[20] Previous studies in Sudan showed the existence of measles vaccine hesitancy is attributed to different drivers including vaccination access-related issues such as the parental perception that measles vaccination services are unavailable and inaccessible [7,21]. Additionally, a study found that the uptake of the measles vaccine among children is predicted by their parental hesitancy toward the measles vaccine [22].…”

Section: Introductionmentioning

confidence: 99%

Perceived Vaccine Access Issues and the Uptake of Measles Vaccine in Sudan: The Mediating Role of Vaccination Hesitancy

Sabahelzain¹,

Tagelsir²,

Elhadi³

et al. 2022

Preprint

Self Cite

View full text Add to dashboard Cite

Background: This study aimed to evaluate whether measles vaccine uptake can be predicted directly or indirectly by parental perceptions about the availability of measles vaccine services with parental hesitancy towards the measles vaccine as a potential mediator. Methods: This was a community-based cross-sectional study conducted at Omdurman locality in Khartoum state, Sudan in February 2019. The study population included parents/ guardians having at least one child aged 2 -3 years old. Mediation analysis was conducted using two models, the ordinary least squares path analysis and multiple logistic regression. Results: a total of 495 responded and the mean age of the mothers who participated in the study was 31.1 (SD=5.73). A half of the respondents (50.1%) completed university education and nearly three-quarters of the respondents (74.7%) were housewives. After controlling for the other factors, including the mother’s age and the number of children, parental perception about the accessibility and availability of the measles vaccine influences the uptake of the measles vaccine indirectly through the mediation effect of measles vaccine hesitancy. Conclusions: We suggest that intervening in measles vaccine hesitancy in addition to measles vaccination access issues will have positive impact on the uptake and coverage of the measles vaccine in Sudan.

show abstract

Vaccine Hesitancy among Parents and Its Association with the Uptake of Measles Vaccine in Urban Settings in Khartoum State, Sudan

Cited by 17 publications

References 42 publications

Essential childhood immunization in 43 low- and middle-income countries: Analysis of spatial trends and socioeconomic inequalities in vaccine coverage

Essential childhood immunization in 43 low- and middle-income countries: Analysis of spatial trends and socioeconomic inequalities in vaccine coverage

Perceived Vaccine Availability and the Uptake of Measles Vaccine in Sudan: The Mediating Role of Vaccination Hesitancy

Perceived Vaccine Access Issues and the Uptake of Measles Vaccine in Sudan: The Mediating Role of Vaccination Hesitancy

Contact Info

Product

Resources

About