The COVID-19 vaccination program continues to be intensified around the world to control widespread coronavirus which continues to mutate. Indonesia affected by COVID-19 and currently accelerating vaccination to the entire population throughout the archipelago in achieving herd immunity. The biggest challenge experienced by Indonesia at this moment is delivering COVID-19 vaccination during the event of natural disasters that continue to occur during 2020-2021 pandemic. This article written based on a review of legitimate Indonesian government sources, supported by research articles and official online news published in English and Indonesian language. The review indicated that Indonesian government committed to accelerate the vaccination with various measures. The Indonesian government's policy, Presidential Decree no. 99 year 2020 specified the provision and implementation of COVID-19 vaccine and initialization of the program across all regions. The government synergizes with community, while cross-sectoral collaboration highly visible upon the developed strategies amid disasters events. The strategies include mapping of disaster area, execute vaccinations in disaster areas, involving military and police in the national vaccine program, and introductory of proactive vaccination procedure by taking advantages of central public facilities for vaccination venue and involvement of health students serving as the vaccinator team. The results of this hard work have been proven to stimulate positive impact since Indonesia's vaccination rate has beyond the WHO target. 93.86% of the Indonesian population have received first dose vaccination, while 75.67% completed two-doses and 9.52% received third dose of COVID-19 vaccine. Indonesia is shifting the country status from pandemic to endemic.