Encyclopedia of Bioinformatics and Computational Biology 2019
DOI: 10.1016/b978-0-12-809633-8.20100-3
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Vaccine Target Discovery

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Cited by 17 publications
(15 citation statements)
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“…This is further exacerbated when the conservation is extended to other family members, a consideration given the possibility of APLs as a result of similar genomic architecture between family members [29, 76]. For example, DENV and HIV-1 had 44 and 78 highly conserved sequences each, respectively, however, only 27 and 74 were conserved across majority of the family members [77]. The remaining were either not present in the family members or were represented with conservation that fluctuated from low to high between the members.…”
Section: Discussionmentioning
confidence: 99%
“…This is further exacerbated when the conservation is extended to other family members, a consideration given the possibility of APLs as a result of similar genomic architecture between family members [29, 76]. For example, DENV and HIV-1 had 44 and 78 highly conserved sequences each, respectively, however, only 27 and 74 were conserved across majority of the family members [77]. The remaining were either not present in the family members or were represented with conservation that fluctuated from low to high between the members.…”
Section: Discussionmentioning
confidence: 99%
“…Prediction of epitope-based vaccines using computational tools have been successfully reported against the Chikungunya virus, Zika virus, Ebola virus, Herpes simplex virus, Yellow fever virus, etc. [ 43 , 44 , 45 , 46 , 47 ]. The focus of this study was to predict both B-cell and T-cell epitopes using the S protein of SARS-CoV-2 by immunoinformatics method.…”
Section: Discussionmentioning
confidence: 99%
“…Reverse vaccinology has successfully been used for developing vaccines to fight against many viruses i.e., the Zika virus, Chikungunya virus etc. [101] [102].…”
Section: Origin Of Coronavirus Their Morphology Pathology and Othersmentioning
confidence: 99%