Vaccines against Morbillivirus Infections

Vries, Petra de; Osterhaus, Albert D. M. E.

doi:10.1007/978-1-4613-9226-2_6

Cited by 3 publications

(2 citation statements)

References 45 publications

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“…Within the genus Morbillivirus of the family Paramyxoviridae, five different viruses have been recognised, which infect members of different mammalian orders under natural conditions: measles virus (MV) of humans, canine distemper virus (CDV) of dogs and other carnivores, rinderpest virus (RPV) and peste des petits ruminants virus (PPRV) of artiodactyls [4,7]. The fifth member of the genus, phocid distemper virus-1 (PDV-1) [21], caused a devastating epizootic among the harbour seals (Phoca vitulina) of North Western Europe in 1988 [18,19], PDV-1 proved to be antigenically and genetically closely related to CDV [13,15,24].…”

Section: Summary Morbillivirus Were Isolated From Mediterranean Strimentioning

confidence: 99%

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Dolphin morbillivirus infection in different parts of the Mediterranean Sea

Bressem

Visser²,

Swart³

et al. 1993

Archives of Virology

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Section: Summary Morbillivirus Were Isolated From Mediterranean Strimentioning

confidence: 99%

“…phocoena) stranded on the and Dutch coasts [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. In the summer of 1990, a morbillivirus associated die-off occurred among the striped dolphins (Stenelta coeruteoalba) of the western part of the Mediterranean Sea [1,5,8,22].…”

mentioning

confidence: 99%

Dolphin morbillivirus infection in different parts of the Mediterranean Sea

Bressem

Visser²,

Swart³

et al. 1993

Archives of Virology

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Measles Vaccines: Novel Generations And New Strategies

Osterhaus¹,

Vries²,

Binnendijk³

1994

Journal of Infectious Diseases

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Although the introduction of live attenuated measles vaccines in industrialized countries in the 1960s has largely contributed to the control of measles, the disease remains a major cause of serious disease and mortality in many developing countries. This is largely because of low vaccine coverage and interference by maternally derived antibodies. To overcome these problems, new vaccination strategies and novel generations of vaccines should be developed. Among the approaches presently considered are the use of different routes of application of new attenuated measles and recombinant viruses and of viral subunits presented with new adjuvant systems. To evaluate the potential of these new approaches in terms of protective mechanisms, efficacy, and safety, a recently evaluated macaque model of measles virus infection may be expected to be a potent tool.

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