The strong and complex vibration from a manipulator for anchor drilling will damage the key components of the manipulator and produce noise at the same time. According to its vibration characteristics, a fluid–spring vibration absorption approach with five degrees of freedom (DOFs) is proposed, which has perfect symmetry, and a vibration absorber was designed with a symmetrical structure. Employing the generalization formula of the Bernoulli equation and dynamic equation, a fluid–spring coupling damping coefficient equation was constructed. Vibration transmissibility was used as the evaluation index of vibration absorption performance. The elastic coefficients of the tension spring and torsion spring, the area ratio of circular through-holes to the vibration-absorbing plate, and the radius of circular through-holes were the main independent factors influencing the damping coefficients. An orthogonal experiment with four factors and four levels was designed. Using FLUENT and SIMULATION to implement joint simulations, the distribution law of the flow fields and the damping coefficients of each approach were obtained, and then the best combination of factors was selected. Taking a manipulator used for anchor drilling in Huainan of China as a case study, using the designed fluid–spring vibration absorber, the vibration displacements in the five DOFs were reduced by 68.32%, 49.82%, 52.17%, 49.01%, and 57.09% respectively, indicating a good vibration absorption performance with symmetry about the z→-axis.