(Knox, 1961). Since the original work of Knox and Penikett (1958) on the level of forevacuum to be employed in high pre-vacuum sterilization no detailed confirmation of their results has been presented, although suggestive supportive evidence is available (Magee and Oakes, 1958;Alder and Gillespie, 1959; Wells and Whitwell, 1960).A high pre-vacuum contributes to the efficient steam sterilization of dressings, i.e., a process which produces a dry, sterile load in the shortest possible time without damage to the load. Other factors which contribute to efficiency are effective drying of the load with which must be bracketed a good supply of dry, saturated steam, prevention of the load being recontaminated by unsterile air at the end of the process, and finally any modification to a sterilizer which increases its rate of turnover.In the present study the factors concerned with the efficiency of such sterilizers which have been considered are: Speed of sterilization in relation to whether a sterilizer should be jacketed or unjacketed,