The open string on the plane-wave limit of dS n × S n with constant B 2 and dilaton background fields is canonically quantized. This entails solving the classical equations of motion for the string, computing the symplectic form, and defining from its inverse the canonical commutation relations. Canonical quantization is proved to be perfectly suited for this task, since the symplectic form is unambiguously defined and non-singular. The string position and the string momentum operators are shown to satisfy equal-time canonical commutation relations. Noticeably the string position operators define non-commutative spaces for all values of the string worldsheet parameter σ, thus extending non-commutativity outside the branes on which the string endpoints may be assumed to move. The Minkowski spacetime limit is smooth and reproduces the results in the literature, in particular non-commutativity gets confined to the endpoints.