Vaginal agenesis and vaginal dilation: an individualized approach using three-dimensional (3D) printer molds.

Abstract

Objective: The aim of this study was to evaluate the use of vaginal molds, made with three-dimensional (3D) printing, for conservative treatment through vaginal dilation in patients with Vaginal Agenesis (VA). Methods: Sixteen patients with a diagnosis of VA (Mayer-Rokitansky-Küster-Hauser syndrome, Total Androgen Insensitivity Syndrome and cervicovaginal agenesis), from Federal University of São Paulo, were selected. The production of the devices was carried out in a 3D printer and, as raw material, the polymeric filament of the lactic polyacid (PLA) was used. A personalized treatment was proposed and developed for each patient.Results: Fourteen patients reached a final vaginal length of 6 cm or more. The initial TVL Mean (SD) was 1,81(1,05) and the final TVL Mean (SD) 6,37(0,94); the Difference (IC-95%) was 4,56 (5,27 - 3,84) and the Effect size (IC-95%) was 4,58 (2,88 – 6,28). Therefore, there was a significant difference (P<0.05) between the initial and final measurements. The Effect Size was 4.58, reinforcing the great magnitude of this difference. Conclusion: The present study has shown the fruitful applicability of the devices, which offers an economical, accessible, promissing and reproducible strategy for the treatment of VA.

The Use of Three-dimensional Printer Molds for Treatment of Vaginal Agenesis

“…According to a study by Fernandes et al 5 published in the current issue, the application of this technology in the production of dilators for vaginal agenesis proved to be effective, economically viable, accessible and reproducible. Therefore, dilators can be produced in a gynecological care service equipped with a 3D printer and a qualified professional, allowing women with vaginal agenesis to have access to the recommended treatment for their condition.…”