Vaginal discharge: evaluation of syndromic management in Chhattisgarh Institute of Medical Sciences, Bilaspur, C.G.

Abstract

Background:Vaginal discharge is one of the most common problems faced by women. It may be physiological or pathological. Most of the time it caused by bacteria, fungi or parasites and many times these infections are sexually transmitted. Thus it is important to treat vaginal discharge as syndrome. Syndromic management is an inexpensive and effective method to treat vaginal discharge and no preliminary laboratory test are required. We have studied 300 patients attending OPD with complain of vaginal discharge to access the efficiency, acceptability and tolerance of one day combination kit therapy (azithromycin 1 g, fluconazole 150 mg and Secnidazole 2 g). Methods: Three hundred women were selected randomly with the complaint of vaginal discharge. They were examined thoroughly and advised to take one day kit therapy. Their partners were also advised to take same therapy. They were called after two weeks to know about their symptoms and for examination. Results: Sixty percent women had excellent response for vaginal discharge, 75% women had excellent response for urinary symptoms and 77.3% women had excellent response for pruritus vulvae. Conclusions: The combination kit therapy in vaginal discharge allows a simple and fast assured therapy, with high cure rate for vaginal discharge.

A Clinical Study to Assess the Effectiveness of Oral Combination Kit Therapy in Syndromic Management of Abnormal Vaginal Discharge (FEMINE Study) in Kinshasa, Democratic Republic of Congo

“…Our results are similar to those found by Venugopal et al [20], Fanou et al [21], Sylla et al [22] and Pizzorno et al [23]. Whitish discharge is characteristic of vulvaginal candidiasis, and according to literature, latter remains one of main causes of abnormal vaginal discharge worldwide [1]…”

“…Several authors are unanimous that trichomonas vaginalis, vulvovaginal candidiasis, and bacterial vaginosis are most common causes of pathological vaginal discharge [4] [7] [29]. Thus, due to polymicrobial nature of abnormal vaginal discharge [30], combined kit based on secnidazole, Azithromycin and Fluconazole (Azimyn FS Kit) has a significant efficacy and safety profile.…”

“…About 20% -25% of women who visit gynecology department complain of vaginal discharge and leucorrhoea. Although in a few cases the discharge may be a physiological increase in normal vaginal secretion, in over 60% of cases it is due to infection of the vagina and/or cervix [1]. Trichomonas vaginalis, bacterial vaginosis and Candida albicans are the most common causes of pathological vaginal discharge.…”

Rationale of Cross-Sectional Descriptive Study on Clinical Effectiveness of Oral Combination Therapy Based on Secnidazole, Azithromycin and Fluconazole in Syndromic Treatment of Abnormal Vaginal Discharge in Kinshasa/DR Congo

“…About 20% -25% of women who visit gynecology department complain of vaginal discharge and leukorrhea. Although, in some cases, discharge may be a physiological increase in normal vaginal secretion, in more than 60% of cases it is due to infection of the vagina and/or cervix [1]. This is second most common problem after abnormal uterine bleeding.…”