Vaginal Fibrosarcoma in Golden Retriever Dog: Case Report

Abstract

A Golden Retriever bitch, 10 years old, came to the Animal Hospital of Brawijaya University, Malang, Indonesia, her conditions was discharge from the vagina, stink smell, polyuria, polydipsia and swelling in the vaginal area that begin to appear one month ago. Physical examination results found her weight 30 kg, scored three for body condition score (scale 1-5), body temperature at 38ºC, pale mucous membrane, and Capillart Reill Time > 2 seconds. Hard mass was palpable in the vaginal area. Based on the anamnesis, physical examination and clinical symptoms, the bitch appeared have some different diagnosis such as pyometra, endometritis, vaginitis, and vaginal tumors. Hematology, radiograph, and histopathological laboratory tests were performed to confirm the diagnosis. Hematologic results showed the bitch suffered from leukocytosis of 41.7 x 103/?L, granulocytosis 36.5 x 103/?L, and hyperchromic microcytic anemia. The results of the radiograph examination showed a radiopaque solid mass in the vagina and uterus. The results of the histopathological examination found there were hyperchromasia nuclei and pleomorphism of fibroblast cell, and formation spindles cell of connective tissue. Based on the results of physical examination, hematological test, radiographic test, and histopathology, the dog was diagnosed with fibrosarcoma in the vagina. The treatment of this case was ovariohysterectomy and removal of the vaginal tumor. Early diagnosis and early treatment largely determine the patient’s prognosis, metastatic vaginal fibrosarcoma tumors showed poor prognosis.

Excision of prolapsed vaginal fibroma in a Golden Retriever dog

“…Histopathologically, vaginal fibromas consist of fusiform or oval-shaped fibroblast tumor cells with oval nuclei and easily recognizable cell structures (Figure 2). These findings were consistent with those reported by Suartha et al (2020). Fibrosarcoma is characterized by pleomorphism, hyperchromasia, karyomegaly, spindle cells with elongated oval nuclei, and connective tissue (Fauzi et al 2021).…”

“…These findings were consistent with those reported by Suartha et al (2020). Fibrosarcoma is characterized by pleomorphism, hyperchromasia, karyomegaly, spindle cells with elongated oval nuclei, and connective tissue (Fauzi et al 2021).…”

“…Large, hard fibromas can obstruct the vagina, impede urination, and cause excessive straining, potentially leading to prolapse. While difficulty urinating due to fibroma has been reported, prolapse has not (Suartha et al 2020).…”

“…Fibroma is a benign tumor of fibroblast cells that often occurs in soft tissue, dermis, and subcutaneous tissue. Fibroma in the cervix of Golden Retriever dogs has been reported in Indonesia (Suartha et al 2020), and fibrosarcoma in the vagina (Fauzi et al 2021). While vaginal fibroma cases are frequently encountered by practicing veterinarians, incident reports in Indonesia are still rare.…”