Vaginal misoprostol versus vaginal surgical evacuation of first trimester incomplete abortion: Comparative study

Shokry, Mahmoud; Fathalla, Mahmoud F.; Hussien, Mostafa; Eissa, Ashraf

doi:10.1016/j.mefs.2013.05.007

Cited by 12 publications

(17 citation statements)

References 17 publications

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“…8 SHOKY also reported 79.6% success with misoprostol and 100 % in surgical evacuation. 9 (p value= 0.0006) study conducted in Indian scenario by Beenuet et al, found medical method to be effective in 92% patients. 10 Adisso et al recorded 99 % success in medical management.…”

Section: Discussionmentioning

confidence: 96%

“…Mdshoky et al also found similar tolerability in the two groups. 9 Tolerability was also high in the study at Madagascar and Maldova which was conducted on 300 women. 8 They found it to highly tolerable method rates being 75%.…”

mentioning

confidence: 95%

“…Shokey et al found that bleeding was more with misoprostol treatment being of statistical significance (p value 0.0336). 9 In study by Adisso et al, 5 % patients in the medical group experienced heavy bleeding. 11 All patients but 2 (grand multigravidas) complained of excruciating pain during and after the procedure.…”

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confidence: 95%

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A comparative study of misoprostol versus surgical management of incomplete and missed miscarriage

Verma

Thakur

Awasiya

2016

Int J Reprod Contracept Obstet Gynecol

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Section: Discussionmentioning

confidence: 96%

mentioning

confidence: 95%

See 1 more Smart Citation

A comparative study of misoprostol versus surgical management of incomplete and missed miscarriage

Verma

Thakur

Awasiya

2016

Int J Reprod Contracept Obstet Gynecol

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“…Some of these conditions, particularly induced abortion, can be managed by medical therapy as an alternative to surgery. However, evidence shows superior outcomes from surgery, including studies from LMICs . Surgical backup is crucial in case the treatment is unsuccessful.…”

Section: Methodsmentioning

confidence: 99%

Surgically avertable burden of obstetric conditions in low‐ and middle‐income regions: a modelled analysis

Higashi

Barendregt

Kassebaum

et al. 2014

BJOG

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Objective To quantify the burden of maternal and neonatal conditions in low-and middle-income countries (LMICs) that could be averted by full access to quality first-level obstetric surgical procedures.Design Burden of disease and epidemiological modelling.Setting LMICs from all global regions.Population The entire population in 2010.Methods We included five conditions in our analysis: maternal haemorrhage; obstructed labour; obstetric fistula; abortion 1 ; and neonatal encephalopathy. Demographic and epidemiological data were obtained from the Global Burden of Disease 2010 study. We split the disability-adjusted life years (DALYs) of these conditions into surgically 'avertable' and 'non-avertable' burdens. We applied the lowest age-specific fatality rates from all global regions to each LMIC region to estimate the avertable deaths, assuming that the differences of death rates between each region and the lowest rates reflect the gap in surgical care. Main outcome measures Deaths and DALYs avertable.Results Of the estimated 56.6 million DALYs (i.e. 56.6 million years of healthy life lost) of the selected five conditions, 21.1 million DALYs (37%) are avertable by full coverage of quality obstetric surgery in LMICs. The avertable burden in absolute term is substantial given the size of burden of these conditions in LMICs. Neonatal encephalopathy constitutes the largest portion of avertable burden (16.2 million DALYs) among the five conditions, followed by abortion (2.1 million DALYs).Conclusions Improving access to quality surgical care at first-level hospitals could reduce a tremendous burden of maternal and neonatal conditions in LMICs.

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“…The side effects associated with misoprostol are similar to that in other studies. 7,8 Only one case in this study required transfusion due to heavy bleeding. Rests of the side effects were minor.…”

Section: Figure 1: Induction Abortion Intervalmentioning

confidence: 84%

An observational study to evaluate fall in hemoglobin following abortions conducted by misoprostol and surgical methods

Das¹,

Wilson²,

Xess³

2020

Int J Reprod Contracept Obstet Gynecol

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Background: Over the past three decades, medical methods of abortion have been developed throughout the world and are now the standard methods of providing abortion care in addition to surgical methods. There are various differences between the two methods. In this study, evaluating the fall in haemoglobin levels in abortions conducted by misoprostol and D and E in women with pregnancy failure.Methods: Total of 80 women who fulfilled the criteria were included in the study. Inclusion and exclusion criteria applied and Hb levels noted on day 1 and 15 during follow up. In addition to this induction abortion interval and side effects of both the methods were also studied. Participants assigned to medical treatment received 800 μg of misoprostol inserted into posterior vaginal fornix i.e., day 1st and repeat dose on day 3 if no expulsion. Follow up done after 1 week and 15 days, if there was no expulsion, suction and evacuation was done. Participants assigned to dilatation and evacuation group would undergo the procedure in operation theatre. Statistical analysis done.Results: The mean induction to abortion interval in the misoprostol group was 9.1±2.1 hours (mean±SD). The mean hemoglobin level in the misoprostol group on day 15 was 9.7±1.12 and that in the D and E group was 10.26±1.31 p value (0.04), statistically significant.Conclusions: Proper counseling of the side effects in both the methods and prompt action to alarming signs are required to avoid major disaster.

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Vaginal misoprostol versus vaginal surgical evacuation of first trimester incomplete abortion: Comparative study

Cited by 12 publications

References 17 publications

A comparative study of misoprostol versus surgical management of incomplete and missed miscarriage

A comparative study of misoprostol versus surgical management of incomplete and missed miscarriage

Surgically avertable burden of obstetric conditions in low‐ and middle‐income regions: a modelled analysis

An observational study to evaluate fall in hemoglobin following abortions conducted by misoprostol and surgical methods

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