Vaginitis in women, diagnosis and treatment

Clinical Spectrum of Desquamative Inflammatory Vaginitis

“…Subsequent cases were presented by Scheffey et al [2] (1956), Gray and Barnes [3] (1965), and Gardner [4] (1968), describing women with normal estrogen levels and features of exudative vaginitis and severe atrophic vaginitis: fragility, erythema, and copious discharge. However, many of the clinical features described by Gray and Barnes and by Gardner were noted to resemble vaginal lichen planus in later case reports and reviews by others [5][6][7][8].…”

Desquamative inflammatory vaginitis

“…By contrast, specialized studies in vulvovaginal clinics estimate the incidence of DIV as 0.8e4.3% of referred cases. This incidence likely reflects a referral or accrual bias [5,6,7]. The etiology is unknown.…”

“…Cultures were sent for all six patients and two were positive for Trichomonas vaginalis. [7] The authors concluded that the other four had an "interesting form of vaginitis … seems to represent a clinical entity … and the true nature is not clear." [7] The definition was refined only 3 years later when Gardner published his milestone case series of eight patients titled "Desquamative inflammatory vaginitis: a newly defined entity."…”

“…[7] The authors concluded that the other four had an "interesting form of vaginitis … seems to represent a clinical entity … and the true nature is not clear." [7] The definition was refined only 3 years later when Gardner published his milestone case series of eight patients titled "Desquamative inflammatory vaginitis: a newly defined entity." [3] All eight patients presented with purulent discharge and demonstrated ecchymotic vaginal spotting and desquamation of vaginal walls.…”

Vulval Disease from the 1800s to the New Millennium

“…Later, patients with a vaginal discharge and a thin hyperemic vaginal mucosa were described. 7,8 The term``d esquamative in¯ammatory vaginitis'' was introduced to describe these patients, and eight further cases were added in 1968. 9 Several reports followed and authors believed that desquamative in¯ammatory vaginitis was, in fact, erosive lichen planus.…”