vaginitis: Transmission from yeast used in baking

Nyirjesy, Paul; Vázquez, José Antonio; Ufberg, David; Sobel, Jack D.; Boikov, Dina; Buckley, Helen R.

doi:10.1016/0029-7844(95)00174-p

Cited by 34 publications

(22 citation statements)

References 4 publications

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“…All clinical strains collected from patients not treated with S. boulardii exhibited a distinct pattern, with the exception of isolates collected from the same patients and a cluster of four isolates collected from French patients that shared their pattern with that of a commercial baker yeast. In this case it may be postulated that the colonization of the patients results from the use of this strain in the diet, as has already been shown in another study (23).…”

Section: Discussionmentioning

confidence: 54%

Microsatellite Typing as a New Tool for Identification of Saccharomyces cerevisiae Strains

et al. 2001

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Since Saccharomyces cerevisiae appears to be an emerging pathogen, there is a need for a valuable molecular marker able to distinguish among strains. In this work, we investigated the potential value of microsatellite length polymorphism with a panel of 91 isolates, including 41 clinical isolates, 14 laboratory strains, and 28 strains with industrial relevance. Testing seven polymorphic regions (five trinucleotide repeats and two dinucleotide repeats) in a subgroup of 58 unrelated strains identified a total of 69 alleles (6 to 13 per locus) giving 52 different patterns with a discriminatory power of 99.03%. We found a cluster of clinical isolates sharing their genotype with a bakery strain, suggesting a digestive colonization following ingestion of this strain with diet. With the exception of this cluster of isolates and isolates collected from the same patient or from patients treated with Saccharomyces boulardii, all clinical isolates gave different and unique patterns. The genotypes are stable, and the method is reproducible. The possibility to make the method portable is of great interest for further studies using this technique. This work shows the possibility to readily identify S. boulardii (a strain increasingly isolated from invasive infections) using a unique and specific microsatellite allele.

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Section: Discussionmentioning

confidence: 54%

Microsatellite Typing as a New Tool for Identification of Saccharomyces cerevisiae Strains

et al. 2001

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“…The ability of clinical S. cerevisiae isolates to adhere to epithelial cells may represent a novel virulence factor. In particular, adherence may be important in cases where the vagina [5,6] or oropharynx [28] are colonized by this yeast. Adherence to epithelial tissue has previously been shown to be crucial for the successful colonization of these body sites by C. albicans [15].…”

Section: Control Cellsmentioning

confidence: 99%

“…There have been numerous reports of S. cerevisiae inducing disease in both healthy and immunocompromised individuals [1] and the yeast has been found in many diverse body sites including the lungs [2][3][4], the liver and blood [2], oesophagus, scrotum and urine [4]. S. cerevisiae has also been found to be the aetiological agent of vaginitis in a number of instances [5,6]. S. cerevisiae has recently been upgraded from 'generally regarded as safe' (GRAS) status to biosafety level one (BSL-1) status [7].…”

Section: Introductionmentioning

confidence: 99%

Adherence of clinical isolates of Saccharomyces cerevisiae to buccal epithelial cells

Murphy

Kavanagh

2001

Med Mycol

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A number of isolates of Saccharomyces cerevisiae have been associated with disease in immunocompromised individuals. Such isolates display a variety of characteristics that enable colonization and persistence in the host. The aim of the work presented here was to establish whether clinical isolates of S. cerevisiae were capable of adhering to epithelial tissue. Adherence to host tissue has been shown to be crucial to the virulence of the pathogenic yeast Candida albicans, and identi cation of this ability in S. cerevisiae might indicate a role for adherence in tissue colonization by this emerging pathogen. Clinical S. cerevisiae isolates were found to be capable of adhering to exfoliated buccal epithelial cells (BECs) but to a lesser degree than C. albicans. In contrast to the situation evident with C. albicans, the adherence of S. cerevisiae isolates to BECs was not in uenced by the carbon source in which the yeast was grown. Treatment of S. cerevisiae with trypsin or proteinase K resulted in a signi cant reduction in adherence ability while adherence was unaffected by treatment of cells with mannosidase, thus indicating a possible role for proteins rather than mannoproteins in the adherence of S. cerevisiae to BECs.

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“…C. dubliniensis is a newly discovered variant of C. albicans 12 . Saccharomyces cerevisiae is another isolate found in vaginitis cases 13 .…”

Section: Introductionmentioning

confidence: 99%

Facts and myths on recurrent vulvovaginal candidosis—a review on epidemiology, clinical manifestations, diagnosis, pathogenesis and therapy

Rodrigues²,

et al. 2002

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Summary:Approximately three-quarters of all women will experience an episode of vulvovaginal candidosis at least once in their life and 5± 10% of them will have more than one attack. Women suffering from three to four attacks within 12 months will be diagnosed with recurrent vulvovaginal candidosis (RVVC). This review covers the large number of proposed aetiological factors for RVVC. The diagnosis of the condition made by conventional means by health providers is often false and is also often misdiagnosed by the affected woman herself. The review covers various methods of diagnosing RVVC and the current knowledge on potential pathogenetic mechanisms proposed for genital candida infections. Treatment of RVVC, including local and systemic antimicrobial therapy and behaviour modi® cation to decrease the risk of recurrences, are discussed. Recent knowledge on drug resistance in candida is also included.

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vaginitis: Transmission from yeast used in baking

Abstract: Saccharomyces cerevisiae vaginitis can be the result of the inoculation of this yeast from exogenous sources.

Cited by 34 publications

References 4 publications

Microsatellite Typing as a New Tool for Identification of Saccharomyces cerevisiae Strains

Microsatellite Typing as a New Tool for Identification of Saccharomyces cerevisiae Strains

Adherence of clinical isolates of Saccharomyces cerevisiae to buccal epithelial cells

Facts and myths on recurrent vulvovaginal candidosis—a review on epidemiology, clinical manifestations, diagnosis, pathogenesis and therapy

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