Vagus nerve signal has an inhibitory influence on the development of peritoneal metastasis in murine gastric cancer
Yurie Futoh,
Hideyo Miyato,
Hironori Yamaguchi
et al.
Abstract:The vagus nerve is the only pathway for transmitting parasympathetic signals between the brain and thoracoabdominal organs, thereby exhibiting anti-inflammatory functions through the cholinergic anti-inflammatory pathway. Despite often being resected during lymph node dissection in upper gastrointestinal cancer surgery, the impact of vagotomy on postoperative outcomes in gastric cancer patients remains unclear. Sub-diaphragmatic vagotomy was performed on C57BL/6 mice. Three weeks later, syngeneic murine gastri… Show more
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