“…Furthermore, the involvement of sternal irrigation after dissection of left internal thoracic artery, right or both, in patients with low tissue perfusion consequent to a state of low cardiac output, also facilitate the action of bacteria [17]. Recent studies indicate that the male patient is more prone to develop mediastinitis and is an independent risk factor for its development [18][19][20]. In the present study, as well as that published by Sá et al [21], there was a higher incidence of mediastinitis in male patients.…”