Validación de las ecuaciones propuestas por la Iniciativa Global de Función Pulmonar (GLI) y las de Todas las Edades para espirometría forzada en preescolares sanos españoles

Vicente, Carlos Martín de; Messa, Inés de Mir; Amigό, Sandra Rovira; Vernetta, Alba Torrent; Gartner, Sílvia; Serrano, Ignacio Iglesias; Lezcano, Antonio Carrascosa; Moreno‐Galdó, Antonio

doi:10.1016/j.arbres.2017.07.019

Cited by 12 publications

(1 citation statement)

References 32 publications

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“…It is simple to execute for those who are well instructed and is routinely performed by health care professionals, for example, in primary care or during health examinations of workers [21,22]. A comparison of the values obtained in the test with the theoretical values, estimated from validated formulas (according to age, sex, height, etc), provides information on the lung condition [23,24]. It is, therefore, an essential public health tool for primary, secondary, and tertiary prevention of pathologies with a high impact on the population [25].…”

Section: Lung Dysfunction and Metsmentioning

confidence: 99%

The Impact of Metabolic Syndrome Risk Factors on Lung Function Impairment: Cross-Sectional Study

Molina-Luque,

Molina-Recio,

de-Pedro–Jiménez

et al. 2023

JMIR Public Health Surveill

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Background Metabolic syndrome (MetS) is a constellation of risk factors increasingly present in the world’s population. People with this syndrome are at an increased risk of cardiovascular disease and type 2 diabetes mellitus. Moreover, evidence has shown that it affects different organs. MetS and its risk factors are independently associated with impaired lung function, which can be quantified through spirometric variables. Objective This study aims to determine whether a high number of MetS criteria is associated with increased lung function decline. Methods We conducted a descriptive cross-sectional study with a random sample of 1980 workers. Workers with acute respiratory pathology (eg, influenza), chronic respiratory pathology (eg, chronic bronchitis), or exposure to substances harmful to the lungs (eg, organic and inorganic dust) were not included. MetS was established based on harmonized criteria, and lung function was assessed according to spirometric variables. On the basis of these, classification into restrictive lung disease (RLD), obstructive lung disease, and mixed lung disease (MLD) was performed. In addition, the association between MetS and lung function was established based on analysis of covariance, linear trend analysis, and multiple linear regression. Results MetS was associated with worse lung function according to all the spirometric parameters analyzed (percentage of predicted forced expiratory volume in 1 second: mean 83, SD 13.8 vs mean 89.2, SD 12.8; P<.001 and percentage of predicted forced vital capacity: mean 85.9, SD 11.6 vs mean 92, SD 11.3; P<.001). Moreover, those diagnosed with MetS had a higher prevalence of lung dysfunction (41% vs 21.9%; P<.001), RLD (23.4% vs 11.2%; P<.001), and MLD (7.3% vs 2.2%; P<.001). Furthermore, an increasing number of MetS criteria was associated with a greater impairment of pulmonary mechanics (P<.001). Similarly, with an increasing number of MetS criteria, there was a significant linear trend (P<.001) in the growth of the prevalence ratio of RLD (0 criteria: 1, 1: 1.46, 2: 1.52, 3: 2.53, 4: 2.97, and 5: 5.34) and MLD (0 criteria: 1, 1: 2.68, 2: 6.18, 3: 9.69, and 4: 11.37). Regression analysis showed that the alteration of all MetS risk factors, adjusted for various explanatory variables, was significantly associated with a worsening of spirometric parameters, except for forced expiratory volume in 1 second/forced vital capacity. Conclusions The findings have shown that an increase in cardiometabolic risk factors is associated with a more significant worsening of spirometric variables and a higher prevalence of RLD and MLD. As spirometry could be a crucial tool for monitoring patients at risk of developing chronic pathologies, we conclude that this inexpensive and easily accessible test could help detect changes in lung function in patients with cardiometabolic disorders. This highlights the need to consider the importance of cardiometabolic health in lung function when formulating public health policies.

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Section: Lung Dysfunction and Metsmentioning

confidence: 99%