The rise in greenhouse gas concentrations has been identified as a primary driver of global warming, leading to adverse effects such as rising sea levels and droughts. In response, understanding the dynamics of greenhouse gas concentration changes has become pivotal in the quest to effectively combat climate change and mitigate the adverse effects of global warming. This study utilizes data from the GOSAT satellite to analyze the trends in global CO2 and CH4 concentrations from 2010 to 2022. Furthermore, the time series and seasonal variation characteristics of greenhouse gas concentrations of CO2 and CH4 in the Hefei area were studied, combined with the geographical environment of Hefei. To enhance comprehension, the article also assembles an HYSPLIT backward trajectory model to scrutinize the latent influences exerted by monsoon transport and atmospheric boundary layer conditions on greenhouse gas distributions. Over the course of the decade from 2010 to 2022, greenhouse gas concentrations in the Hefei region exhibited an unwavering upward trajectory, punctuated by conspicuous seasonal fluctuations, showcasing distinct seasonal variations that aligned with the observations of the ground-based observation network TCCON. The concentrations of CO2 surged from 391.05 ppm to 417.98ppm, signifying a net gain of 26.930ppm, corresponding to an annual growth rate of approximately 2.4 ppm. Similarly, CH4 concentrations underwent a net increase of 72 ppb, characterizing an annual growth rate of about 10.4 ppb. These figures underscore the relentless ascent of greenhouse gas concentrations, warranting immediate attention and action. The concentrations of greenhouse gases are subjected to a plethora of factors, encompassing both local biogenic and non-biogenic sources, the intricate patterns of monsoon-driven atmospheric transport, and the unique characteristics of the atmospheric boundary layer. The findings emanating from this comprehensive study are poised to serve as the bedrock upon which Hefei City can formulate and refine its strategies for greenhouse gas emission reduction. Furthermore, the study emphasizes the impact of monsoon transport patterns and atmospheric boundary layer conditions, which can significantly affect the dispersion and accumulation of greenhouse gases in the region. Understanding these factors is crucial for devising effective strategies to mitigate greenhouse gas emissions.