Validation of a Life Quality (LQ) Test for asthma

Winder, John; Nash, Kent D.; Brunn, Julie Winder

doi:10.1016/s1081-1206(10)62573-2

Cited by 26 publications

(15 citation statements)

References 1 publication

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“…All subjects received a validated self-administered asthma and rhinitis screening questionnaire, with 20 questions adopted from the American College of Allergy, Asthma & Immunology screening program extended with questions concerning tobacco consumption. 15 At the clinic, all participants had their fraction of exhaled nitric oxide (FENO) and lung function values measured, a skin prick test and a BPT with inhaled mannitol were performed, and reversibility to inhaled b 2 -agonists was recorded. In line with international guidelines on bronchial provocation, all participants were told to withhold use of antiasthmatic drugs before the examination.…”

Section: Methodsmentioning

confidence: 99%

Diagnostic properties of inhaled mannitol in the diagnosis of asthma: A population study

Sverrild

Porsbjerg

Thomsen

et al. 2009

Journal of Allergy and Clinical Immunology

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Section: Methodsmentioning

confidence: 99%

Diagnostic properties of inhaled mannitol in the diagnosis of asthma: A population study

Sverrild

Porsbjerg

Thomsen

et al. 2009

Journal of Allergy and Clinical Immunology

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“…A total of 300 subjects with asthma, as defined by the American College of Allergy, Asthma and Immunology asthma questionnaire, 41 were recruited. The subjects were randomized to standard asthma Greater improvement in lung function, symptoms, and quality of life was observed in the intervention group.…”

Section: How Can We Improve Adherence To Ics? Which Interventions Work?mentioning

confidence: 99%

Asthma and Adherence to Inhaled Corticosteroids: Current Status and Future Perspectives

2014

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Inhaled corticosteroids (ICS) are the cornerstone of maintenance asthma therapy. However, in spite of this, adherence to ICS remains low. The aim of this systematic literature review was to provide an overview of the current knowledge of adherence to ICS, effects of poor adherence, and means to improve adherence. A total of 19 studies met the inclusion criteria: 9 focusing on the level of adherence, 6 focusing on effects of poor adherence, and 7 focusing on interventions to improve adherence. Three of the studies focused on more than one of these end points. The mean level of adherence to ICS was found to be between 22 and 63%, with improvement up to and after an exacerbation. Poor adherence was associated with youth, being African-American, having mild asthma, < 12 y of formal education, and poor communication with the health-care provider, whereas improved adherence was associated with being prescribed fixed-combination therapy (ICS and long-acting ␤ 2 agonists). Good adherence was associated with higher FEV 1 , a lower percentage of eosinophils in sputum, reduction in hospitalizations, less use of oral corticosteroids, and lower mortality rate. Overall, 24% of exacerbations and 60% of asthmarelated hospitalizations could be attributed to poor adherence. Most studies have reported an increase in adherence following focused interventions, followed by an improvement in quality of life, symptoms, FEV 1 , and oral corticosteroid use. However, 2 studies found no difference in health-care utilization, one observed no effect on symptoms, and one observed more symptoms in subjects in the intervention group compared with the control group. Good adherence to ICS in asthma improves outcome but remains low. Interventions to improve adherence show varying results, with most studies reporting an increase in adherence but unfortunately not necessarily an improvement in outcome. Even following successful interventions, adherence remains low. Further research is needed to explore barriers to adherence and interventions for improvement.

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“…All subjects received a validated selfadministered asthma and rhinitis screening questionnaire with 20 questions adopted from the American College of Allergy, Asthma, and Immunology screening program extended with questions concerning tobacco consumption. 9 All participants attended 1 study visit, which included (in order of execution) measurement of eNO at a rate of 50 mL/min, lung function measurement, a skin prick test, a BPT with inhaled mannitol, a BPT with methacholine, and a reversibility test to an inhaled b 2 -agonist. The results of the methacholine test have been shown not to be influenced by the performance of a previous mannitol test, 10 and this test was performed when the subjects had reached a level of 95% of their baseline FEV 1 .…”

mentioning

confidence: 99%

Airway hyperresponsiveness to mannitol and methacholine and exhaled nitric oxide: A random-sample population study

Sverrild

Porsbjerg

Thomsen

et al. 2010

Journal of Allergy and Clinical Immunology

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Validation of a Life Quality (LQ) Test for asthma

Cited by 26 publications

References 1 publication

Diagnostic properties of inhaled mannitol in the diagnosis of asthma: A population study

Diagnostic properties of inhaled mannitol in the diagnosis of asthma: A population study

Asthma and Adherence to Inhaled Corticosteroids: Current Status and Future Perspectives

Airway hyperresponsiveness to mannitol and methacholine and exhaled nitric oxide: A random-sample population study

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