“…Among 21 articles, 15 papers had a low risk of bias [ 1 , 6 , 11 , 13 , 18 , 25 , 29 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 ], four articles displayed some level of unclear risk of bias [ 12 , 17 , 28 , 42 ], and two articles had a high risk of bias [ 15 , 43 ]. Considering applicability concerns, 13 articles exhibited a low level of concern [ 1 , 6 , 11 , 12 , 13 , 25 , 34 , 35 , 36 , 38 , 39 , 40 , 41 ], two articles showed an unclear level of concern [ 17 , 28 ], and six articles showed a high level of concern [ 15 , 18 , 29 , 37 , 42 , 43 ]. Major bias was found in the patient selection domain because some studies were not clear in method to provide random samples or used a small number of included volunteers/patients [ 11 , 15 , 18 , 34 , 41 , 42 , 43 ].…”