Validation of a new risk score system for non-variceal upper gastrointestinal bleeding

Abstract

Background: Recently, a new international bleeding score was developed to predict 30-day hospital mortality in patients with upper gastrointestinal bleeding (UGIB). However, the efficacy of this newly developed scoring system has not been extensively investigated. We aimed to validate a new scoring system for predicting 30-day mortality in patients with non-variceal UGIB and determine whether a higher score is associated with re-bleeding, length of hospital stay, and endoscopic failure. Methods: A retrospective study was performed on 905 patients with acute non-variceal UGIB who were examined in our hospital between January 2013 and December 2017. Baseline characteristics, endoscopic findings, rebleeding, admission, and mortality were reviewed. The 30-day mortality rate of the new international bleeding risk score was calculated using the receiver operating characteristic curves and compared to the pre-endoscopy Rockall score, AIMS65, Glasgow Blatchford score, and Progetto Nazionale Emorragia Digestiva score. To verify the variable for the 30-day mortality of the new scoring system, we performed multivariate logistic regression using our data and further analyzed the score items. Results: The new international bleeding scoring system showed higher receiver operating characteristic (ROC) curve values in predicting mortality (area under ROC curve 0.958; [95% confidence interval (CI)]), compared with such as AIMS65 (

Evaluation of Six Preendoscopy Scoring Systems to Predict Outcomes for Older Adults with Upper Gastrointestinal Bleeding

“…Regarding mortality and intervention, GBS was superior to AIMS65, pRS, and T -score. However, GBS showed poor performance for rebleeding, which is similar to a previous study [ 27 ]. As mentioned in the Asian-Pacific Consensus Group guideline 2018 [ 28 ], GBS does not accurately predict rebleeding.…”

Comparisons of six endoscopy independent scoring systems for the prediction of clinical outcomes for elderly and younger patients with upper gastrointestinal bleeding

“…In our research cohort, GBS showed the best ability to predict the need for ICU admission for elderly patients (Table 6 ). Except for rebleeding (poor accuracy for the elderly group and moderate accuracy for the younger group), GBS showed acceptable performances for both groups (Tables 3 , 4 , 5 ), which is like the results reported by Kim et al [ 26 ]. As mentioned in the Asian-Pacific Consensus Group guideline 2018 [ 17 ], it is challenging for GBS to predict rebleeding accurately.…”

Comparison of intermittent and continuous proton pump inhibitor infusions in patients with non-variceal upper gastrointestinal bleeding at King Abdulaziz University Hospital, Jeddah, Saudi Arabia

“…Fresh hematemesis or melena accompanied with the development of shock (pulse >100 beats/min, systolic blood pressure 100 mmHg) or a drop in haemoglobin concentration >2 g/dL for >24 hours were considered rebleeding. 13 The length of hospital stays was defined as the date of hospital admission to discharge. Finally, all-cause in-hospital mortality is any death occurring during admission within 30 days.…”