Validation of a population coronary disease predictive system: the CASSANDRA model

Grau, María; Subirana, Isaac; Vila, Joan; Elosúa, Roberto; Ramos, Rafael; Sala, Joan; Dégano, Irene R.; Tresserras, Ricard; Bielsa, Oscar; Marrugat, Jaume

doi:10.1136/jech-2013-203516

Cited by 4 publications

(1 citation statement)

References 41 publications

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“…The observed increase in DALY rates with advancing age, as reported in our study, reflects patterns noted in cross-sectional and demographic-specific studies [41][42][43]. These patterns are not isolated but are echoed by the GBD 2015 and the CASSANDRA model, which underscore the importance of age in understanding the CVD epidemiology and projecting disease burden [44,45]. Moreover, our data correspond with findings from diverse population studies, such as those conducted on geriatric populations in India and on postmenopausal women, further substantiating age as a pivotal determinant of CVD burden [46,47].…”

Section: Discussionsupporting

confidence: 80%

The burden of Cardiovascular diseases in Jordan: a longitudinal analysis from the global burden of disease study, 1990–2019

Al-Ajlouni,

Al Ta’ani,

Shamaileh

et al. 2024

BMC Public Health

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Background Cardiovascular Disease (CVD) is the leading cause of mortality worldwide. While countries in the Arab world continue to lack public health data and be severely understudied in health research, previous research has shown that compared to 1990, CVDs had a higher burden of disease in the Arab World in 2010. Jordan, a middle-income Arab country, is profiled with unique attributes such as a dual-sector healthcare system, political stability, and its role as a haven for refugees and migrants. These distinctive factors emphasize Jordan’s suitability as a case study. This investigation aims to quantify CVD burden in Jordan and identify risk factors, contributing to a broader understanding of health challenges in the Arab region and beyond. Methods The Global Burden of Disease (GBD) dataset was used to estimate prevalence, death, and disability-adjusted life-years (DALYs) as age-standardized rates from 1990 to 2019. We calculated percentage change for nine specific CVDs and reported trends by gender and age groups. Additionally, data on twelve a priori selected behavioral, clinical, and environmental risk factors attributing to overall age-standardized CVDs DALY were reported per 100,00 population. Results In 2019, the age-standardized CVD prevalence, death, and DALYs rates in Jordan were 7980 (95% uncertainty interval [UI] 7629, 8360), 248 (95% UI 211, 288), and 4647 (95% UI 4028, 5388), respectively. Despite an increase in the absolute number of mortality and prevalence, between 1990 and 2019, the age-standardized prevalence, death, and DALYs rates all decreased by 5.5%, 45.1%, and 46.7%, respectively. In 2019, the leading risk factors contributing to overall age-standardized CVDs DALY per 100,000 population were high systolic blood pressure, high BMI, dietary risks, and high LDL cholesterol. Conclusion Despite decreasing burden rate of CVDs in Jordan between 1990 and 2019, CVDs remain the leading cause of mortality in Jordan, with an increase in the total number of prevalence and mortality. Overall, this contributes to increased healthcare costs. Further research is required to quantify the burden of CVDs and understand it better. Intervention measures and policies tailored to specific CVDs should be designed to reduce the burden of CVDs in Jordan.

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Section: Discussionsupporting

confidence: 80%

The burden of Cardiovascular diseases in Jordan: a longitudinal analysis from the global burden of disease study, 1990–2019

Al-Ajlouni,

Al Ta’ani,

Shamaileh

et al. 2024

BMC Public Health

View full text Add to dashboard Cite

show abstract

Theoretical Impact on Coronary Disease of Using a Computerized Clinical Decision Support System in the Prescription of Lipid-lowering Treatment

Zamora

Carrión

Vázquez-Oliva

et al. 2015

Revista Española de Cardiología (English Edition)

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Impacto teórico en la enfermedad coronaria de usar un sistema informatizado de ayuda en la prescripción del tratamiento hipolipemiante

Zamora

Carrión

Vázquez-Oliva

et al. 2015

Revista Española de Cardiología

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Validation of a population coronary disease predictive system: the CASSANDRA model

Abstract: The CASSANDRA model produces valid estimates, particularly in men, of the future burden of disease and in the distribution of cardiovascular risk in individuals aged 35-74 years.

Cited by 4 publications

References 41 publications

The burden of Cardiovascular diseases in Jordan: a longitudinal analysis from the global burden of disease study, 1990–2019

The burden of Cardiovascular diseases in Jordan: a longitudinal analysis from the global burden of disease study, 1990–2019

Theoretical Impact on Coronary Disease of Using a Computerized Clinical Decision Support System in the Prescription of Lipid-lowering Treatment

Impacto teórico en la enfermedad coronaria de usar un sistema informatizado de ayuda en la prescripción del tratamiento hipolipemiante

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