Validation of a single-use and reusable home sleep apnea test based on peripheral arterial tonometry compared to laboratory polysomnography for the diagnosis of obstructive sleep apnea

Lyne, Christopher; Hamilton, Garun S.; Turton, Anthony; Stupar, Durda; Mansfield, Darren

doi:10.5664/jcsm.10568

Cited by 8 publications

(2 citation statements)

References 20 publications

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“…Peripheral artery tonometry-based devices combine information on changes in arterial volume with oxygen saturation (SpO 2 ; both from the PPG signal) with data on peripheral arterial tone and heart rate (Yalamanchali et al, 2013;Massie et al, 2018;Van Pee et al, 2022;Lyne et al, 2023). During recording, a respiratory event is typically detected by analyzing the co-occurrence of one or more of the following events: oxygen desaturation; vasoconstriction (decreased peripheral artery tonometry signal); and increased pulse rate.…”

Section: Photoplethysmography and Peripheral Arterial Tonometry For D...mentioning

confidence: 99%

Novel Technologies in the Diagnosis and Management of Sleep-disordered Breathing

2024

Frontiers Research Topics

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Frontiers is more than just an open access publisher of scholarly articles: it is a pioneering approach to the world of academia, radically improving the way scholarly research is managed. The grand vision of Frontiers is a world where all people have an equal opportunity to seek, share and generate knowledge. Frontiers provides immediate and permanent online open access to all its publications, but this alone is not enough to realize our grand goals. Frontiers journal seriesThe Frontiers journal series is a multi-tier and interdisciplinary set of openaccess, online journals, promising a paradigm shift from the current review, selection and dissemination processes in academic publishing. All Frontiers journals are driven by researchers for researchers; therefore, they constitute a service to the scholarly community. At the same time, the Frontiers journal series operates on a revolutionary invention, the tiered publishing system, initially addressing specific communities of scholars, and gradually climbing up to broader public understanding, thus serving the interests of the lay society, too. Dedication to qualityEach Frontiers article is a landmark of the highest quality, thanks to genuinely collaborative interactions between authors and review editors, who include some of the world's best academicians. Research must be certified by peers before entering a stream of knowledge that may eventually reach the public -and shape society; therefore, Frontiers only applies the most rigorous and unbiased reviews. Frontiers revolutionizes research publishing by freely delivering the most outstanding research, evaluated with no bias from both the academic and social point of view. By applying the most advanced information technologies, Frontiers is catapulting scholarly publishing into a new generation. What are Frontiers Research Topics?Frontiers Research Topics are very popular trademarks of the Frontiers journals series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area.

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Section: Photoplethysmography and Peripheral Arterial Tonometry For D...mentioning

confidence: 99%

Novel Technologies in the Diagnosis and Management of Sleep-disordered Breathing

2024

Frontiers Research Topics

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Section: Photoplethysmography and Peripheral Arterial Tonometry For D...mentioning

confidence: 99%

A new approach to streamline obstructive sleep apnea therapy access using peripheral arterial tone-based home sleep test devices

Zou,

Vits,

Egea

et al. 2023

Front. Sleep

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Obstructive sleep apnea (OSA) is a prevalent condition that negatively impacts cardiovascular, metabolic and mental health. A high proportion of individuals with OSA remain undiagnosed and incur significant healthcare costs. The gold standard OSA diagnostic is in-lab polysomnography, but this is costly and time-consuming. Home sleep apnea tests (HSATs), including cardiorespiratory polygraphy and peripheral artery tonometry technology, provide an alternative. Advances in HSAT technology include non-invasive, easy-to-use medical devices that could allow unobtrusive, accessible, multi-night, cost-effective diagnosis and management of sleep-disordered breathing. One type of these devices is based on determination of peripheral arterial tone, and use photoplethysmography signals from the finger (oxygen saturation, pulse wave amplitude and pulse rate). The devices contain algorithms that use these data to generate the traditional metrics required by the American Academy of Sleep Medicine. They can be used to record sleep parameters over multiple nights at home, and can also provide information on total sleep time (TST) and sleep stages (including time spent in rapid eye movement sleep). The combination of objective measures (apnea-hypopnea index, oxygen desaturation index, respiratory disturbance index, TST) and subjective measures (symptoms and other patient-reported outcome measures) could facilitate the development of a personalized therapeutic plan for OSA patients. It is anticipated that the streamlined digital pathway facilitated by new peripheral artery tone-based technology could contribute to reducing the underdiagnosis of OSA, accelerating access to appropriate treatment, and the optimization of OSA therapy.

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Immediate Postoperative Changes After Expansion Pharyngoplasty and Hypoglossal Nerve Stimulation

Yu,

Wong,

Cook

et al. 2024

The Laryngoscope

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ObjectivePatients with obstructive sleep apnea (OSA) are at an increased risk for perioperative cardiopulmonary complications. Our objective was to assess the postoperative effects of hypoglossal nerve stimulation implantation (HGNS) and expansion pharyngoplasty (EP) on longitudinal sleep apnea measures as a surrogate for respiratory complications.Study DesignProspective longitudinal cohort study of patients with OSA undergoing HGNS or EP.MethodsSleep studies were performed with the NightOwl Mini peripheral arterial tonometry (PAT) device. Changes in apnea‐hypopnea index (AHI) and oximetry time below 90% (T90) were assessed between two baseline PAT studies prior to surgery and nightly PAT studies for the first postoperative nights (PON) 1–7, 10, and 14.ResultsThirty patients were enrolled (19 HGNS, 11 EP). The mean age was 52.6 years, 76.7% were male, and the mean clinical baseline AHI was 29.8/h. There were no significant changes in the AHI or T90 following HGNS implantation. Following EP, there was a statistically significant mean increase in AHI of +19.2/h on PON1, +24.9/h on PON2, and + 20/h on PON3 compared to baseline. T90 was also elevated after EP on PON1, 4, and 5. The mean increase in T90 was +7.4% (95% CI 2.9, 11.9) on PON1 compared to baseline.ConclusionsIn the immediate postoperative period, there were no significant changes in AHI or hypoxemia after HGNS, suggesting that there is no need for routine overnight observation after HGNS. There were significant increases in AHI and hypoxemia after EP suggesting that postoperative disposition should be considered on a case‐by‐case basis.Level of EvidenceIII Laryngoscope, 2024

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Validation of a single-use and reusable home sleep apnea test based on peripheral arterial tonometry compared to laboratory polysomnography for the diagnosis of obstructive sleep apnea

Cited by 8 publications

References 20 publications

Novel Technologies in the Diagnosis and Management of Sleep-disordered Breathing

Novel Technologies in the Diagnosis and Management of Sleep-disordered Breathing

A new approach to streamline obstructive sleep apnea therapy access using peripheral arterial tone-based home sleep test devices

Immediate Postoperative Changes After Expansion Pharyngoplasty and Hypoglossal Nerve Stimulation

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