Validation of Acute Myocardial Infarction Cases in the National Health Insurance Research Database in Taiwan

Cheng, Ching Lan; Lee, Cheng‐Han; Chen, Po Sheng; Li, Yi Heng; Lin, Shio Jean; Yang, Yea Huei Kao

doi:10.2188/jea.je20140076

Cited by 431 publications

(349 citation statements)

References 28 publications

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“…The accuracy of the NHIRD has been validated in many aspects of clinical studies [15][16][17]. All adult patients who were hospitalized with a primary diagnosis of gastric cancer [International Classification of Diseases, Ninth Edition, Clinical Modification (ICD-9-CM) code 151] for the first time and had undergone gastrectomy without cholecystectomy between 1 January 2000 and 31 December 2011 comprised the study population ( Table 1).…”

Section: Patients and Study Designmentioning

confidence: 99%

Analysis of gallstone disease after gastric cancer surgery

et al. 2017

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Background The incidence rate of newly developed gallstone disease after gastrectomy for gastric cancer is thought to be higher than that in the general population. However, the presentation and management of these gallstones remain under debate, and the role of prophylactic cholecystectomy remains questionable. Methods Data on adult patients who were diagnosed with gastric cancer and received gastrectomy between 2000 and 2011 were extracted from the Taiwan National Health Insurance Research Database. A patient was excluded if he or she had gallstone disease or received cholecystectomy before the index date. The incidence of newly developed gallstone disease and its subsequent management were recorded. Data were analyzed to evaluate the factors associated with gallstone development and treatment options. Results A total of 17,325 gastric cancer patients who underwent gastrectomy were eligible for analysis. During the follow-up period (mean 4.1 years; median, 2.9 years), 1280 (7.4%) patients developed gallstone disease and 560 (3.2%) patients subsequently underwent cholecystectomy. The in-hospital mortality for cholecystectomy was 1.8% (10/560). Development of gallstone disease was associated with older age, total gastrectomy, duodenal exclusion, diabetes, cirrhosis, and more comorbidities. Factors associated with the use of cholecystectomy to treat gallstone disease included younger age, fewer comorbidities, medical center admission, and presentation as cholecystitis. Conclusions Although few patients required further gallbladder removal after gastrectomy for gastric malignancy, the increased mortality rate for subsequent cholecystectomy was worth noting. The decision to undergo prophylactic cholecystectomy might be individualized based upon patient characteristics and the surgeon's discretion.

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Section: Patients and Study Designmentioning

confidence: 99%

Analysis of gallstone disease after gastric cancer surgery

et al. 2017

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“…The accuracy of diagnostic coding of myocardial infarction and ischemic stroke in the NHIRD database has been reported to be as high as 93% and 94%, respectively. 23,24 The secondary outcomes were hospital admission with the principal diagnosis of acute kidney injury (ICD-9-CM code 584.x) or hyperkalemia (ICD-9-CM code 276.7) during follow-up. All patients were followed until death or Dec. 31, 2012.…”

Section: Discussionmentioning

confidence: 99%

Comparative effectiveness of angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers in patients with type 2 diabetes and retinopathy

Shih

Chen

Kuo

et al. 2016

CMAJ

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Background: Angiotensin-converting-enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) are effective treatments for diabetic retinopathy, but randomized trials and meta-analyses comparing their effects on macrovascular complications have yielded conflicting results. We compared the effectiveness of these drugs in patients with pre-existing diabetic retinopathy in a large populationbased cohort. Methods:We conducted a propensity scorematched cohort study using Taiwan's National Health Insurance Research Database. We included adult patients prescribed an ACE inhibitor or ARB within 90 days after diagnosis of diabetic retinopathy between 2000 and 2010. Primary outcomes were all-cause death and major adverse cardiovascular events (myocardial infarction, ischemic stroke or cardiovascular death). Secondary outcomes were hospital admissions with acute kidney injury or hyperkalemia. Results

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“…The BNHI database maintains a nationwide database covering 99.68% of the Taiwan population [17]. The database has been reported to have up to 94% accuracy [2,3]. Moreover, several hundred publications have been based on the data.…”

Section: Methodsmentioning

confidence: 99%

Risk of Post-TKA Acute Myocardial Infarction in Patients With a History of Myocardial Infarction or Coronary Stent

Kumar

Tsai

Tan

et al. 2016

Clinical Orthopaedics &Amp; Related Research

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Background Acute myocardial infarction (AMI) is one of the most important perioperative complications of total knee arthroplasty (TKA). Although risk-stratification tools exist for the prediction of cardiac complications including AMI after noncardiac surgery, such stratification does not differentiate the patients with a coronary stent alone, AMI without a stent, or AMI with a stent. The risk of postoperative AMI in these patient groups may vary. Several studies have recommended suitable times for noncardiac surgery in patients with a coronary stent; however, they do not differentiate between the patients with AMI and no AMI. The suitable time of noncardiac surgery for patients with AMI and stent may vary from those with a stent alone. Moreover, a study to evaluate the risk of AMI within 1 year in an Asian population with a history of AMI or coronary stent who underwent TKA has not been reported. Questions/purposes (1) What are the risks of AMI within 1 year of TKA in patients who have had a stent alone, AMI without a stent, or AMI with a stent as compared with patients without an AMI/stent? (2) For patients with AMI/ stent placement, when can TKA be performed where the risk of subsequent AMI normalizes? (3) What comorbidities are associated with post-TKA AMI? (4) Is the risk of AMI within 1 year after surgery in patients undergoing TKA without a history of AMI/stent higher than that in patients with no surgery? Methods This study is a retrospective study of the medical claim records of 128,216 patients who underwent TKA between 1997 and 2010 in Taiwan. The records were retrieved from the research database of the Bureau of National Health Insurance in Taiwan, which maintains the records of 99.68% of the Taiwan population. The patients who had a history of AMI or coronary stent placement within the year before TKA were compared with the patients who had not experienced AMI or stent placement before TKA. The control subjects were matched according to sex, age, Charlson score, and year of surgery. There were 2413 patients in each group. The patients with a history of AMI or stent placement and the timing of TKA after coronary event were further stratified as with a coronary stent alone, AMI without a stent, and AMI with a Each author certifies that he or she, or a member of his or her immediate family, has no funding or commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article. Conclusions This study found the risk of post-TKA AMI remains high within 1 year in patients with a history of AMI/stent. It is recommended that an elective TKA should be performed at least 1 year after an episode of AMI or stent placement. Stents do not provide protection against post-TKA AMI within 6 months of the AMI and patients with AMI + stent have a higher risk of AMI than those with only AMI. Patients of AMI/stent on hemodialysis have a very high risk of post-TKA AMI. However, the risk of AM...

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Validation of Acute Myocardial Infarction Cases in the National Health Insurance Research Database in Taiwan

Cited by 431 publications

References 28 publications

Analysis of gallstone disease after gastric cancer surgery

Analysis of gallstone disease after gastric cancer surgery

Comparative effectiveness of angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers in patients with type 2 diabetes and retinopathy

Risk of Post-TKA Acute Myocardial Infarction in Patients With a History of Myocardial Infarction or Coronary Stent

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