Validation of an anatomy specific finite element model of Colles’ fracture

Варга, П.; Baumbach, Sebastian Felix; Pahr, Dieter H.; Zysset, Philippe

doi:10.1016/j.jbiomech.2009.04.017

Cited by 68 publications

(38 citation statements)

References 43 publications

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“…HR-pQCT-based FE models (nominal resolution equal to 82 μm) have been already validated with experimental tests of human vertebral bodies [45]. While homogenization techniques are recently applied to high resolution images in order to take account of trabecular microstructure and cortical thickness [38,45,46], the μFE models, in which the voxels of the CT image are directly converted in hexahedral elements, remain the gold standard [47][48][49]. Despite the well represented geometry and microstructure of the vertebra, a large number of degrees of freedom are included in the analysis (in the order of 100 mil for a vertebral body section [45]).…”

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confidence: 99%

QCT-based finite element models predict human vertebral strength in vitro significantly better than simulated DEXA

et al. 2011

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confidence: 99%

QCT-based finite element models predict human vertebral strength in vitro significantly better than simulated DEXA

et al. 2011

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“…First, in some of the literature studies, only a model of the intact distal radius was analyzed and the focus was determination of failure load of the distal radius [33] [34] or prediction of Colles' fracture load [35] [36]. In other words, these studies were conducted to investigate bone mechanics and fracture (especially, the role played by bone mineral density in these aspects) rather than within the context of evaluation of surgical fixation of DRFs.…”

Section: Discussionmentioning

confidence: 99%

Finite Element Analysis Study of Prototype of a Novel Intramedullary Injectable Bioresorbable Polymer Fixator versus a Volar Plate for Surgical Treatment of Distal Radius Fractures

Zysk¹,

Lewis²

2017

WJET

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Complications and shortcomings of volar plating, which is very widely used for surgical treatment of distal radius fractures, are well known. Thus, there is scope for alternative innovative surgical methods. In the present work, we used the finite element analysis method to compare the biomechanical performance of a model of a construct comprising a simulated distal radius fracture considered fixated using a notional intramedullary injectable bioresorbable polymer-bioresorbable balloon osteosynthesis system ("fixator") versus using a commercially-available volar locking plate (VP). The biomechanical parameters determined were longitudinal stiffness and factor of safety under each of the applied loads. For the fixator model, 1) each of the biomechanical parameters was markedly influenced by fracture gap fill ratio (FGFR) (defined as the proportion of the volume of the fracture gap that is considered occupied by the expanded polymer-filled balloon) but not by modulus of elasticity assigned to the polymer; 2) with FGFR = 100%, stiffness was comparable to that of the Ti-6Al-4V alloy VP construct model; and 3) stiffness was within the range of literature values for stiffness of constructs comprising simulated fractures in fresh cadaveric distal radii fixated using metal volar locking plate. These results suggest that the fixator may be an alternative modality to metal volar plating and, as such, deserves further evaluation.

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“…Reprinted from Keyak et al (1998), with permission from Elsevier. Varga et al (2009) presented and validated an organ-scale FE model for the human radius based on homogenized mechanical properties of the trabecular bone microstructure as determined from high-resolution computed tomography (CT) measurements. Bone mineral density and the anisotropy of the microarchitecture were quantified at evenly spaced grid points and were used to derive the local nonlinear, anisotropic material properties (Zysset & Curnier 1995;Garcia et al 2009).…”

Section: Organ-level Fe Modelsmentioning

confidence: 99%

“…At the distal radius, MacNeil & Boyd (2008) defined FE models to simulate compression of a subsection of the distal radius between two endplates, thereby neglecting the load pathways via the metacarpal bones. To balance a relevant application of the load and the ability to reliably replicate it in the simulation, Varga et al (2009) compared results from a direct loading of excised radii to the FE simulations. Pistoia et al (2002) attempted to introduce a greater level of detail by modelling the cartilage of the metacarpal bones and applying a distributed force over its surface.…”

Section: Loading Conditionsmentioning

confidence: 99%

Multiscale modelling and nonlinear finite element analysis as clinical tools for the assessment of fracture risk

Christen

Webster

Müller

2010

Phil. Trans. R. Soc. A.

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The risk of osteoporotic fractures is currently estimated based on an assessment of bone mass as measured by dual-energy X-ray absorptiometry. However, patient-specific finite element (FE) simulations that include information from multiple scales have the potential to allow more accurate prognosis. In the past, FE models of bone were limited either in resolution or to the linearization of the mechanical behaviour. Now, nonlinear, high-resolution simulations including the bone microstructure have been made possible by recent advances in simulation methods, computer infrastructure and imaging, allowing the implementation of multiscale modelling schemes. For example, the mechanical loads generated in the musculoskeletal system define the boundary conditions for organ-level, continuum-based FE models, whose nonlinear material properties are derived from microstructural information. Similarly microstructure models include tissuelevel information such as the dynamic behaviour of collagen by modifying the model's constitutive law. This multiscale approach to modelling the mechanics of bone allows a more accurate characterization of bone fracture behaviour. Furthermore, such models could also include the effects of ageing, osteoporosis and drug treatment. Here we present the current state of the art for multiscale modelling and assess its potential to better predict an individual's risk of fracture in a clinical setting.

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Validation of an anatomy specific finite element model of Colles’ fracture

Cited by 68 publications

References 43 publications

QCT-based finite element models predict human vertebral strength in vitro significantly better than simulated DEXA

QCT-based finite element models predict human vertebral strength in vitro significantly better than simulated DEXA

Finite Element Analysis Study of Prototype of a Novel Intramedullary Injectable Bioresorbable Polymer Fixator versus a Volar Plate for Surgical Treatment of Distal Radius Fractures

Multiscale modelling and nonlinear finite element analysis as clinical tools for the assessment of fracture risk

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