2018
DOI: 10.1101/268698
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Validation of Davson’s equation in patients suffering from idiopathic Normal Pressure Hydrocephalus

Abstract: Introduction -The so called Davson's equation relates baseline intracranial pressure (ICP) to resistance to cerebrospinal fluid outflow (Rout), formation of cerebrospinal fluid (I f ) and sagittal sinus pressure (P SS ) There is a controversy over whether this fundamental equation is applicable in patients with normal pressure hydrocephalus (NPH). We investigated the relationship between Rout and ICP and also other compensatory, clinical and demographic parameters in NPH patients.Method -We carried out a retro… Show more

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“…Another contributing factor to the difference in Rout seen between the two groups could be the age of their populations, which differed significantly. A numerical, age-correction formula for Rout is not yet known, however there is evidence to suggest that Rout increases with age [50][51][52][53]. The significantly lower AMP in group A points towards cerebrovascular bed dysfunction [45-47, 54, 55] or decreased intracranial compliance.…”
Section: Comparison Between Tbi and Inph Groupsmentioning
confidence: 99%
“…Another contributing factor to the difference in Rout seen between the two groups could be the age of their populations, which differed significantly. A numerical, age-correction formula for Rout is not yet known, however there is evidence to suggest that Rout increases with age [50][51][52][53]. The significantly lower AMP in group A points towards cerebrovascular bed dysfunction [45-47, 54, 55] or decreased intracranial compliance.…”
Section: Comparison Between Tbi and Inph Groupsmentioning
confidence: 99%