2020
DOI: 10.1186/s12877-020-01788-1
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Validation of “(fr)AGILE”: a quick tool to identify multidimensional frailty in the elderly

Abstract: Background Several tools have been proposed and validated to operationally define frailty. Recently, the Italian Frailty index (IFi), an Italian modified version of Frailty index, has been validated but its use in clinical practice is limited by long time of administration. Therefore, the aim of this study was to create and validate a quick version of the IFi (AGILE). Methods Validation study was performed by administering IFi and AGILE, after a Comprehensive Geriatric Assessment (CGA) in 401 subjects aged 6… Show more

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Cited by 21 publications
(20 citation statements)
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“…Age-related LMM is a multiple factorial geriatric condition that is associated with known age-related conditions [ 5 ]. Despite its prevalence in older population and its impact on patients’ quality of life, cellular and biological processes associated with LMM are not fully investigated.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Age-related LMM is a multiple factorial geriatric condition that is associated with known age-related conditions [ 5 ]. Despite its prevalence in older population and its impact on patients’ quality of life, cellular and biological processes associated with LMM are not fully investigated.…”
Section: Discussionmentioning
confidence: 99%
“…Multiple factors are involved in the development of age-related low muscle mass, including several known age-related factors, such as neuromuscular degeneration, abnormal protein turnover, decreased hormone levels and sensitivity, chronic inflammation, oxidative stress, and lifestyle (nutritional status and physical inactivity) [ 5 ]. Despite the well-described contribution of these factors, current therapies are only limited to lifestyle changes by mainly targeting resistance training and/or protein supplementation [ 6 , 7 ].…”
Section: Introductionmentioning
confidence: 99%
“…frailty), -увеличивает уязвимость пациентов к различным стрессовым факторам из-за кумулятивного снижения функционирования разных резервно-адаптационных физиологических систем. До 80 % больных, перенесших ОКС, имеют астенический синдром [12][13][14].…”
Section: Discussionunclassified
“…Recently, Liguori et al [ 19 ] proposed a quick tool to identify multidimensional frailty in the elderly derived from the Italian Frailty index (IFi), an Italian modified version of Rockwood’s Frailty index, named AGILE (a 10-item tool created starting from the more predictive items of the four domains of frailty investigated by IFi (mental, physical, socioeconomic and nutritional) [ 19 ]. Main domains and tools for frailty evaluation are reported in Table 1 .…”
Section: Frailty: Definition and Modelsmentioning
confidence: 99%