Validation of Parachlorobenzotrifluoride, Benzotrifluoride, and Monochlorotoluene on Diffusive Samplers

Abstract

Three solvents (OXSOL 10, monochlorotoluene or mixed isomers of 1- chloro-2-methyl benzene and 1-chloro-4-methyl benzene; OXSOL 100, parachlorobenzotrifluoride or 1-chloro-4-(trifluoromethyl) benzene; and OXSOL 2000, benzotrifluoride or trifluoromethyl benzene) produced by Occidental Chemical Corporation (Niagara Falls, NY) were considered as candidates for SKC, Inc.'s on-going diffusive sampler validation program. The 575-series diffusive sampler contains coconut-shell charcoal (575-001) or Anasorb 747 (575-002). Both samplers were used in this study. Desorption efficiency was tested at loadings equivalent to eight-hour time-weighted average (TWA) exposures to 0.01-2 times the Occidental Chemical Corporation in-house limit values (respectively: 50 ppm, 25 ppm, and 100 ppm,. All results met the National Institute for Occupational Safety and Health (NIOSH) criteria of > 75 percent, and, except for the lower loadings of parachlorobenzotrifluoride, the results were in the range of 90-110 percent. The calculated uptake rates were verified for different periods of exposure, up to eight hours, and found to be within 5 percent of the calculated for all three compounds on both samplers. A detailed comparison of the results from different time periods indicated no significant reverse diffusion effects for any combination of sampler and analyte. Samplers exposed to standard atmospheres of each compound were stored for three weeks at ambient temperatures and reanalyzed with results between 94 and 107 percent of expected. Based on full validation of samplers for the lower homologue (benzene), the bi-level theory of sample validation as endorsed by international validation protocols establishes this as a complete validation of the featured samplers for sampling vapors of these chemicals in air.

Assessing Exposures to 1-chloro-4-(trifluoromethyl) Benzene (PCBTF) in U.S. Workplaces

“…The NIOSH method has suggested a maximum of 25 ppm for a 10 L air sample with a working range between 0.024 and 9.15 ppm (0.178 to 67.8 mg/m 3 ). Yost and Harper (8) tested passive badges at various loadings in a standard atmosphere chamber in which the test concentrations of the standard atmosphere were confirmed by means of coconut charcoal tubes for time period up to 8 hr. Those loadings were 0.012 mg (0.01×CEL), 0.123 mg (0.1×CEL), 0.505 mg (0.5×CEL), 1.10 mg (1.0×CEL), and 2.09 mg (2.0×CEL).…”

“…Those loadings were 0.012 mg (0.01×CEL), 0.123 mg (0.1×CEL), 0.505 mg (0.5×CEL), 1.10 mg (1.0×CEL), and 2.09 mg (2.0×CEL). Yost and Harper (8) showed charcoal tubes and passive badges to have a large capacity covering up to 2 times the CEL and the maximum concentration suggested by the NIOSH method.…”

“…(8) From each sampling site, 1–10 field blank samples were collected. In this study, sample results were not adjusted by field blank samples because almost all field blank samples (96% of 56 field blank samples) showed non-detectable masses.…”