Validation of Placental Vascular Sonobiopsy for Obtaining Representative Placental Vascular Indices by Three-Dimensional Power Doppler Ultrasonography

Placental volume and three‐dimensional power Doppler analysis in prediction of pre‐eclampsia and small for gestational age between Week 11 and 13 weeks and 6 days of gestation

“…Placental volume was found to be smaller in pregnancies with high pulsatility index (PI) in the uterine artery as well as in women developing pre-eclampsia (Hafner et al, 2006;Rizza et al, 2008), but it was not a good predictor of SGA fetuses (Hafner et al, 1998). Placental volume measurement (Deurloo et al, 2007;Burstein et al, 2009) and 3D-PD indices of the placenta were found reproducible either in the whole volume of the placenta (Bujold et al, 2009;Huster et al, 2010) or by placenta vascular sonobiopsy (Merce et al, 2004(Merce et al, , 2005Tuuli et al, 2010). Guiot et al (2008) reported the use of threedimensional power Doppler (3D-PD) ultrasound to assess the placental perfusion in normal and growthrestricted pregnancies between 23 and 37 weeks of gestation and concluded that 3D-PD can provide new insights into placental pathophysiology.…”

Future Uses of Three/Four Dimensional Power Doppler Signal in Fetal Medicine

“…It seems that the evaluation of first trimester placental vascularisation correlates, somehow, with a compromised placentation and therefore could predict some adverse perinatal outcomes of placental origin. Besides, the technique exhibits fairly good repeatability and accuracy (Tuuli et al 2010;Martins & N J Raine-Fenning 2010;Yigiter et al 2011). …”

Examinations of placental three-dimensional power Doppler indices in pregnancies complicated by diabetes mellitus and intrauterine growth restriction

“…Our study was designed based on a literature search for this issue and our aim was to find a technique, which is applicable even if the whole placenta can not be visualized and irrespectively of the placental volume it can be used throughout the whole pregnancy. The "Mercé-type sonobiopsy" [55] was applied in our study as a well-defined, validated method [66], in which both the intraobserver and interobserver errors are low [52].…”