Validation of Standardized Questionnaires Evaluating Symptoms of Depression in Rheumatoid Arthritis Patients: Approaches to Screening for a Frequent Yet Underrated Challenge

Englbrecht, Matthias; Alten, Rieke; Aringer, Martin; Baerwald, Christoph; Burkhardt, Harald; Eby, Nancy L.; Fliedner, G.; Gauger, Bettina; Henkemeier, U.; Hofmann, Michael; Kleinert, Stefan; Kneitz, Christian; Krueger, Klaus; Pohl, Christoph; Roske, Anne-Eve; Schett, Georg; Schmalzing, Marc; Tausche, Anne‐Kathrin; Tony, Hans Peter; Wendler, J.

doi:10.1002/acr.23002

Cited by 34 publications

(35 citation statements)

References 36 publications

(50 reference statements)

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“…The questionnaire contained the validated German version of the BDI-FS and the validated German version of the Changes in Sexual Functioning Questionnaire (CSFQ-14) 12–14…”

Section: Methodsmentioning

confidence: 99%

Depression: a common comorbidity in women with rheumatoid arthritis—results from an Austrian cross-sectional study

Sautner¹,

Puchner

Alkin³

et al. 2020

BMJ Open

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ObjectivesPrevious research showed that depression is common in rheumatoid arthritis (RA). However, the prevalence very much depends on different assessment tools and sociocultural differences, respectively. The main study aim and research question was to investigate the proportion of depressive symptoms in Austrian female patients with RA.SettingA nationwide multicentre study with seven secondary care centres all over Austria (hospital-based rheumatological outpatient clinics and private practices).Participants319 patients with RA and 306 healthy controls (HCO), all female Caucasians, were asked to complete a Beck’s Depression Inventory–Fast Screen (BDI-FS). Patients and HCO were ≥18 years. Patients had to fulfil the 2010 classification criteria for RA. In addition, disease activity, disability, medication, drinking of alcoholic beverages, smoking and occupational status were evaluated.Primary and secondary outcome measuresA BDI-FS cut-off value of ≥4, per definition, indicates the presence of a depressive symptomatology.ResultsThe return rate of questionnaires was high: 235/319 (73.7%) in patients with RA and 180/306 (58.8%), ending up with 392 complete questionnaires from 223 patients with RA (69.9%) and 169 HCO (55.2%). The BDI-FS was significantly higher in patients with RA (median BDI-FS 2 (IQR 0–4) vs median 1 (IQR 0–2) in HCO, p<0.001). BDI-FS scores from ≥4, which by definition indicate depression, were found in 29.6% of patients with RA and 12.4% of HCO (p<0.001). Depressive symptoms were strongly associated with disease activity (Clinical Disease Activity Index, p<0.001) and disability (Health Assessment Questionnaire, p<0.005). No association of depressive symptoms with age, alcohol consumption, smoking, occupational status or use of medication was found.ConclusionsOne-third of female patients with RA showed depressive symptoms. Depression was significantly higher in female patients with RA than in female HCO and was strongly associated with disease activity and disability. It would be of interest to address the same question in male participants.

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“…The questionnaire contained the validated German version of the BDI-FS and the validated German version of the Changes in Sexual Functioning Questionnaire (CSFQ-14) 12–14…”

Section: Methodsmentioning

confidence: 99%

Depression: a common comorbidity in women with rheumatoid arthritis—results from an Austrian cross-sectional study

Sautner¹,

Puchner

Alkin³

et al. 2020

BMJ Open

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“…Die Praktikabilität wird als gut eingeschätzt, zur Anwendung mit Menschen mit kognitiven Einschränkungen wurden jedoch keine Angaben gefunden (Allgaier et al, 2013;Brähler, Mühlan, Albani & Schmidt, 2007;Schneider et al, 2010). Aufgrund der identifizierten Studien kann die Validität des WHO-5 als akzeptabel beurteilt werden (Allgaier et al, 2013;Brähler et al, 2007;Englbrecht et al, 2017;Heun, Bonsignore, Barkow & Jessen, 2001;Schneider et al, 2010).…”

Section: Who-5 Wohlbefindens-indexunclassified

“…Innere Struktur: angemessene Korrelationen zwischen Items (r=0,37-0,79) und zwischen Items und Gesamtwert (r=0,52-0,82;Brähler et al, 2017;Schneider et al, 2010); gute interne Konsistenz mit Crohnbach's α=0,93 bzw. 0,83 (Allgaier et al, 2013;Schneider et al, 2010) Beziehung zu anderen Variablen (Auswahl): Korrelation mit Fragebogen zur Erfassung des körperlichen Wohlbefindens r=0,56 bis 0,65 (Brähler et al, 2007); mit BDI r=−0,52 bis −0,75 (Englbrecht et al, 2017;Schneider et al, 2010); mit SOMS r=0,53 (Brähler et al, 2007); hohe Spezifizität und Sensitivität bei der Identifikation von Personen mit Depression (Allgaier et al, 2013;Englbrecht et al, 2017;Bonsignore et al, 2001;Schneider et al, 2010) Konsequenzen der Bewertung: k. A. Bullinger et al, 2003;Frosch et al, 2001;Gunzelmann, Albani, Beutel & Brähler, 2006;Maurischat, Ehlebracht-Konig, Kuhn & Bullinger, 2006;Morfeld, Bullinger, Nantke & Brähler, 2005;Novella et al, 2001;Seymour et al, 2001).…”

Section: Short Form Health Survey 36 (Sf-36)unclassified

Assessing the quality of life and well-being of older adults with physical and cognitive impairments in a German-speaking setting: A systematic review of validity and utility of assessments / Die Erfassung von Lebensqualität und Wohlbefinden älterer Menschen mit psychischen und kognitiven Einschränkungen: ein systematisches Literaturreview zur Validität und Praktikabilität deutschsprachiger Assessments

Ballmer

Wirz

Gantschnig

2019

International Journal of Health Professions

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Background For health professionals working with older adults with physical and cognitive impairments, improving or maintaining clients’ quality of life and well-being is of crucial importance. The aim of this study was to evaluate validity and utility of assessments of quality of life and well-being in German suitable for this group of clients. Methods In an initial literature search, we identified potentially viable assessments based on existing systematic reviews. We then conducted a systematic literature search in the databases Medline, CINAHL, and PsycINFO using keywords related to validity, utility, client group, and German. Assessments for which sufficient evidence was found were evaluated regarding their validity and utility when used with older adults with physical and cognitive impairments. Results For 14 of 27 initially identified assessments, sufficient evidence was found to evaluate validity and utility with this client group. WHOQOL-BREF, WHOQOL-OLD, WHO-5, EUROHIS-QOL 8, SF-36, SF-12, EQ-5D, NHP, SEIQOL-DW, SWLS, PANAS, DQOL, QOL-AD, and QUALIDEM were evaluated based on 82 studies. Of these, WHOQOL-BREF, WHO-5, SF-36, SF-12, EQ-5D, NHP, QUALIDEM, QOL-AD and DQOL are presented here. Conclusion Assessments differed widely in the way they operationalized quality of life/well-being, use of self-evaluation or evaluation-by-proxy, and amount of available evidence for their validity and utility. On the basis of our results in regard to the assessments’ validity, utility, and appropriateness of operationalization of quality of life/well-being to the client group, three assessments were recommended for use: WHOQOL-BREF for self-evaluation, QUALIDEM for evaluation-by-proxy in case of severe dementia, and EQ-5D for cost-utility analyses.

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“…Diese Daten entsprechen auch einer multizentrischen Erfassung depressiver Symptome bei 1015 RA-Patienten in Deutschland. Hier fanden sich 20,9 % mit mittelschweren oder schweren depressiven Symptomen nach den gleichen Kriterien [25]. Nach der bisherigen Datenlage ist nicht nur ein Einfluss auf die Lebensqualität sondern auch auf die Adhärenz [26,27] und die Mortalität zu erwarten [24].…”

Section: Depressionunclassified

Komorbiditäten und Mortalität bei Patienten mit entzündlichen Gelenkerkrankungen

Kleinert

2018

Akt Rheumatol

Self Cite

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ZusammenfassungDie entzündlichen Gelenkerkrankungen werden zunehmend als Systemerkrankungen angesehen. Systemische Manifestationen und Komorbiditäten wie kardiovaskuläres Risiko, Fatigue und Depression, Anämie, Osteoporose und erhöhte Mortalität sind in den letzten Jahren zunehmend in den klinischen und wissenschaftlichen Blickpunkt geraten. Infektionsrisiko, chronische Nieren- und Lungenerkrankungen können die Therapie im klinischen Alltag komplizieren. Einschränkungen der Kognition oder der sexuellen Funktion sind dagegen kaum wissenschaftlich erfasst und werden vermutlich auch auf Arzt-Patienten-Ebene unzureichend adressiert. Eine systematische Umsetzung der Erfassung und des Management von Komorbiditäten ist notwendig, um die Mortalität von Patienten mit entzündlichen Systemerkrankungen zu reduzieren und die Lebensqualität zu verbessern. Eine solche Umsetzung wird aber derzeit vom kassenärztlichen System nicht vergütet.

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Validation of Standardized Questionnaires Evaluating Symptoms of Depression in Rheumatoid Arthritis Patients: Approaches to Screening for a Frequent Yet Underrated Challenge

Cited by 34 publications

References 36 publications

Depression: a common comorbidity in women with rheumatoid arthritis—results from an Austrian cross-sectional study

Depression: a common comorbidity in women with rheumatoid arthritis—results from an Austrian cross-sectional study

Komorbiditäten und Mortalität bei Patienten mit entzündlichen Gelenkerkrankungen

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