Abstract. The direct measurement of true maximal• oxygen uptake (VO2max) and oxygen uptake corresponding • to anaerobic threshold (VO2AT) is not always practical, especially in middle age and older populations. Therefore, the purpose of this study was to develop a simple test that could accurately estimate cardiorespiratory fitness using a submaximal treadmill walking protocol for middle age, older, sedentary individuals and patients with chronic disease. Subjects for this study were 42 men (44.9 ± 15.7 years), which included 17 patients with coronary• • heart disease (57.0 ± 9.6 years). VO2peak and VO2AT• were measured using a treadmill protocol (VO2peak; 38.4• ± 11.6 ml/kg/min, VO2AT; 22.9 ± 7.4 ml/kg/min). This simple test assessed the total distance covered in 12 minutes on the treadmill at an intensity corresponding to either 1) 11 on the Borg scale of ratings of perceived exertion (RPE11), 2) 13 on the Borg scale of ratings of perceived exertion (RPE13), or 3) "Optimal" by subjective judgment. The correlation coefficients betweenVO2peak or VO2AT and total distance at the three intensities (RPE11; 950 ± 100 m, RPE13; 1080 ± 140 m Optimal; 1050 ± 110 m) were statistically significant, ranging from 0.72 to 0.85. The test-retest reliability coefficient• on 12 subjects was 0.98. The oxygen uptake (VO2) was measured during the three walk tests on 15 subjects.• There were no significant changes in submaximal VO2 values from min 4 to min 12 (RPE11; 19.8 ± 4.7 ml/kg/ min, RPE13; 24.1 ± 4.9 ml/kg/min, Optimal; 23.1 ± 4.8 ml/kg/min) in any of the three tests. Similarly, the three