Validation of the Chinese Version of Montreal Cognitive Assessment Basic for Screening Mild Cognitive Impairment

Chen, Keliang; Xu, Yan; Chu, Ai-Qun; Ding, Ding; Liang, Xiaoniu; Nasreddine, Ziad; Dong, Qiang; Hong, Zhen; Zhao, Qianhua; Guo, Qihao

doi:10.1111/jgs.14530

Cited by 257 publications

(207 citation statements)

References 27 publications

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“…Daily function was assessed using the Instrumental Activities of Daily Living (IADL) scale [17]. Cognitive function was assessed using the Cognitive Abilities Screening Instrument (CASI) [18] and Montreal Cognitive Assessment (MoCA) [19]. Cognitive tests for all patients were conducted by trained neuropsychologists.…”

Section: Methods and Participantsmentioning

confidence: 99%

An Informant-Based Simple Questionnaire for Language Assessment in Neurodegenerative Disorders

Lin

Hung

Wei

et al. 2018

Dement Geriatr Cogn Disord

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Background/Aims: Language dysfunction is a crucial feature of brain disorders. This study investigated language dysfunction in patients with dementia with or without parkinsonism by using an informant-based simple questionnaire. Methods: Language dysfunction in normal controls (NCs), and patients with Parkinson disease (PD), Parkinson disease dementia (PDD), dementia with Lewy bodies (DLB), or Alzheimer disease (AD) were analyzed and compared. Results: A total of 1,662 individuals were studied: 285 NCs, 157 PD patients, 161 PDD patients, 248 DLB patients, and 811 AD patients. Patients with PD displayed higher frequency of language dysfunction in several language domains than NC. Patients with PDD and DLB showed higher frequency of language dysfunction in most of the language domains than those with AD. A composite score of our simple questionnaire was comparable with the score for the language domain of the Cognitive Abilities Screening Instrument (CASI) in different stages of dementia due to Lewy body diseases or not. Conclusion: Our study showed that the informant-based simple questionnaire is a practical screening tool and is comparable with the language subscale of CASI. This tool can be applied in clinical practice and in the registration platform for rapid language dysfunction screening.

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Section: Methods and Participantsmentioning

confidence: 99%

An Informant-Based Simple Questionnaire for Language Assessment in Neurodegenerative Disorders

Lin

Hung

Wei

et al. 2018

Dement Geriatr Cogn Disord

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“…For details see gure 1 for a owchart. [27]. Details on neuropsychological tests published previously [19].…”

Section: Study Populationmentioning

confidence: 99%

Beneficial impact of education on cognition in amyloid-positive individuals with subjective cognitive decline: The SILCODE study

Chen

Liu

Yang

et al. 2020

Preprint

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Background: Previous studies suggest that education is associated with a decreased risk of dementia in individuals with subjective cognitive decline (SCD). However, the influence of education on cognition in amyloid-positive SCD subjects is not clear.Methods: We performed a cross-sectional study that involved 43 amyloid-negative and 29 amyloid-positive SCD subjects from the Sino Longitudinal Study on Cognitive Decline (SILCODE) project. Cognitive assessment included episodic memory, executive function, language, and general cognitive function. Multiple linear regression model was used to assess the association of education on cognitive performance.Results: Multiple linear regression analysis suggested that education has a protective effect on executive function, language for the amyloid-negative SCD group and language, global cognition for the amyloid-positive SCD group.Conclusions: The present study indicated that education has the potential to delay disease progression in amyloid-positive SCD subjects.

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“…A paper-printed case report form (CRF) was used to record demographic features (name, birthdate, sex, education, occupation, ethnic origin, residential address and contact information etc. ), medical history [26]. To obtain a total test score of cognitive performance, all raw neuropsychological test scores were rst converted into Z scores calculated by subtracting the score from the mean test score and dividing it by the standard deviation of initial test scores, and then the total test score was expressed as a global composite z-scores created by averaging all neuropsychological test z-scores.…”

Section: Clinical and Cognitive Function Assessmentsmentioning

confidence: 99%

APOE ε4 Allele Modulates The Differential Effects of Education on Cognition in Alzheimer’s Continuum: The SILCODE Study

Chen

Yang

Han

2020

Preprint

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Background: Elders with subjective cognitive decline (SCD) in the absence of objective cognitive impairment are at increased risk of developing mild cognitive impairment (MCI) or Alzheimer’s disease (AD). Previous study has reported that higher education was associated with better performance in cognitive performance in elderly people with SCD. However, it is not clear whether there is a differential effect of education on cognition between healthy controls (HC), individuals with SCD and patients with cognitive impairment (CI).Methods: We performed a cross-sectional study that included 186 HC, 279 SCD subjects and 79 patients with CI from the Sino Longitudinal Study on Cognitive Decline (SILCODE) project. A series of neuropsychological tests of memory, executive, language, and general cognitive function were used to assess the subjects cognitive performance. We performed multiple linear regression models to examine the effect of education on neuropsychological test scores in the total sample and then described differences in the effect according to three different groups. In addition, we presented the effect of education on total test score expressed as a global composite z-scores in the total sample and three different groups, respectively. Furthermore, we examined whether apolipoprotein E ε4 allele (APOE ε4) status would regulate the effect of education on the global composite score among three different groups.Results: Education has a positive effect on cognition in the total sample. Stratification for different groups showed that the positive effect of education on cognition is found in HC and SCD group, while education has a negative effect on cognition in the CI group. Furthermore, we found the APOE ε4 allele does not modify the positive effect of education on cognition in the HC group, but the APOE ε4 allele weaken that beneficial effect in the SCD group and maintain the negative effect in the CI group.Conclusions: High education may delay the progression from SCD to cognitive impairment and yield differential effects on cognition across the spectrum of AD. Furthermore, that differential effects are subjected to modulation by the APOE ε4 status.

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Validation of the Chinese Version of Montreal Cognitive Assessment Basic for Screening Mild Cognitive Impairment

Abstract: The MoCA-BC is a reliable cognitive screening test across all education levels in Chinese elderly adults, with high acceptance and good reliability.

Cited by 257 publications

References 27 publications

An Informant-Based Simple Questionnaire for Language Assessment in Neurodegenerative Disorders

An Informant-Based Simple Questionnaire for Language Assessment in Neurodegenerative Disorders

Beneficial impact of education on cognition in amyloid-positive individuals with subjective cognitive decline: The SILCODE study

APOE ε4 Allele Modulates The Differential Effects of Education on Cognition in Alzheimer’s Continuum: The SILCODE Study

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