Migraine-related disability is multidimensional and is poorly appreciated by the diagnostic criteria of the International Society of Headache. The Headache Impact Test-6 (HIT 6) and the Migraine Disability Assessment Questionnaire (MIDAS) are the main scales validated in order to assess the burden associated with migraine. We wanted through this study prospective, transversal, determine the disability associated with migraine in the Mauritanians. The study concerned migraine patients according to the criteria of the International Society of Headache (2013), accepting any treatment. The impact of the disease has been appreciated by the MIDAS and HIT6 scales. Seventy four (74) migrainous have been included. The average age was 30 years and the sex ratio of 3.6 (F/H). All patients have noted a decrease in productivity in relation to migraines. The loss of productivity per quarter was more than 20 days in 78.60% of cases, between 10 and 20 days in 11, 80%, 6-10 days in 6.20% and less than 6 days in 3.40%. The impact of migraine was major in 90, 54% of migraineurs according to the HIT6. The impact of migraine on the quality of life of the Mauritanian patient is huge. Due to the high productivity loss, migraine can be an impediment to the development where the need to encourage physicians to training on the management of pain and put in place support units dedicated to pain.