Validation of the Korean Version of the Biological Rhythms Interview of Assessment in Neuropsychiatry

Abstract

ObjectiveThe Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN) is a scale used to clinically evaluate disturbances in biological rhythm. In this study, we aimed to examine the reliability and validity of the Korean version of the BRIAN (K-BRIAN) in a Korean population. MethodsA total of 181 participants, including 141 outpatients with bipolar disorder (BD; type I, 62; type II, 79) and 40 controls, were recruited. Construct validity was tested by comparing the mean K-BRIAN scores of the BD patients and control subjects. Concurrent validity was tested by evaluating the association between the K-BRIAN and the Morningness-Eveningness Questionnaire (MEQ). ResultsThe mean K-BRIAN scores of the control subjects and patients with BD differed significantly (p<0.001). Particularly, the mean K-BRIAN score was considerably lower among control subjects (mean±standard deviation=35.00±8.88) than among patients with BD type I (41.19±12.10) and type II (50.18±13.73). The Cronbach’s alpha for the K-BRIAN was 0.914. The K-BRIAN was found to correlate with the MEQ (r=-0.45, p<0.001). ConclusionThe findings affirm that the K-BRIAN has good construct validity and internal consistency. This suggests that the K-BRIAN can be used to assess biological rhythms in the Korean population, especially for patients with mood disorder.

Early Onset Depression Has Different Characteristics from Middle-Aged Depression in Terms of Circadian Rhythm

“…Moreover, the mean total BRIAN score of bipolar II disorder in previous studies conducted in Korea [27,33] was close to that of the eMDD group in our study. However, there is no cut-off BRIAN score distinguishing bipolar disorder from MDD, and most individuals in the eMDD group demonstrated a significant amount of biological rhythmic disturbances similar to those with bipolar II disorder.…”

“…These patients were recruited from the psychiatry outpatient clinic of the Korea University Hospital. The HC group comprised 40 individuals recruited from the general population of young adults [27]. All study participants were informed in detail about the purpose and procedures of the study prior to signing an informed consent form.…”

Similarities of Aspects of Biological Rhythms between Major Depression and Bipolar II Disorder Compared to Bipolar I Disorder: A Finding from the Early-Onset Mood Disorder Cohort

“…[23], which classified 138 subjects with BD I, 170 subjects with BD II, and 159 subjects with MDD. 40 control subjects were recruited by matching gender and age from the general population of young adults at Korea University Anam Hospital [21].…”

“…BRIAN consists of 21 items divided into five main areas, related to circadian rhythm disturbance in psychiatric subjects. These five domains are sleep, activities, social-rhythm, eating-pattern, and predominant-rhythm [20], and BRIAN’s validity and reliability have been confirmed for Korean population [21].…”

Association between emotional functioning and biological rhythm disruptions in patients with schizophrenia

“…It also suggested that and subjective measures (BRIAN) provide extensive evidence of sleep and biological rhythm system disruptions in mental disorders [44]. Also, the BRIAN appears to be a feasible tool to evaluate all domain of biological rhythms, due to the other scales that only indirectly measure biological rhythm by testing seasonality or chronotype or subjective quality of sleep [45].…”