Validation of the Lupus Impact Tracker in an Australian patient cohort

Abstract

The LIT demonstrated properties consistent with its being valid in this population. Lower socioeconomic status appears to have a significant impact on patient-reported health-related quality of life in SLE.

The Australian Lupus Registry and Biobank: a timely initiative

“…In addition, biomarker studies examining the interferon‐α gene signature and disease manifestations, response to treatment, vitamin D status and disease manifestations, and patient‐reported quality of life are in the planning stages 9 . ‐ 12 …”

“…In addition, biomarker studies examining the interferon-a gene signature and disease manifestations, response to treatment, vitamin D status and disease manifestations, and patient-reported quality of life are in the planning stages. [9][10][11][12] The registry also collects patient-reported outcomes, such as Short Form 36 and multidimensional health assessment questionnaires. Patients' self-reported data complement physician-reported data in the ALRB to capture the breadth of experiences of patients with SLE in Australia and provide a meaningful assessment of the disease burden and treatment shortfalls.…”

Health‐Related Quality of Life Measures in Adult Systemic Lupus Erythematosus

“…The instrument has been validated in several languages, including German, Italian, Spanish, Swedish, and French . The instrument has also undergone cross‐cultural adaptation and validation in Australia .…”

Oral Hygiene and Dental Caries Status on Systemic Lupus Erythematosus Patients: A Cross-Sectional Study

“…Autoreactive cells escape tolerance mechanisms and enter circulation. The presence of autoreactive B cells is illustrated by the discovery of autoantibodies in peripheral blood circulation [2,4].…”

“…Autoreactive B cells could produce Anti-double stranded DNA (anti-dsDNA). These autoantibodies will form immune complexes and are deposited in the tissues, causing chronic inflammation [4]. SLE patient is vulnerable to infection due to immune dysfunction.…”